DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and sart-3

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_502136.1	Gene:	sart-3 / 178053	WormBaseID:	WBGene00007111	Length:	836	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	89/357 - (24%)
Similarity:	136/357 - (38%)	Gaps:	58/357 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LAKIEKKKAKKQAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVE------KEPTTAPNEK 123
            |.|:..:.|.:..:..||...|.||.....:...|.:........:||:      |.|....|.|
Worm   497 LEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAK 561

  Fly   124 PKGKVSKKAKANANNKDEEG---VKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIR 185
            ....||   .:||::....|   |::.....|:|.|:||.||...|...::.:..:.   |.|||
Worm   562 SSSAVS---SSNASSTPAPGSFAVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEG---VASIR 620

  Fly   186 LRTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFKENHLRVTPASMAEKFGQAKD 250
            ........|. |:.       .||||:|..:.|||||      .|:.    .|......|..|.|
Worm   621 FARKANSDLV-HRG-------FAYVVMENDQKAQQAL------LKDR----VPVKGRPMFISAND 667

  Fly   251 KQP------SDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCF-- 307
            .:.      |....|..:||.::.:.||:::|:.:||..|.:..:|.:...|...||:|:|.|
Worm   668 PEKRVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDT 732

  Fly   308 ----QKPDAVGLALELN----QTLLDDRPINVERYQVK--KLGAKQVRDAAAASAASKTSSKTKA 362
                ||..|.|..|.|.    :..|.:.|:..::...|  .:||....|......|:|.....:|
Worm   733 EASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRA 797

  Fly   363 KNQNSAGAKKRLDKKKGKENGSLKKEGAPTGQ 394
            ....:.....|||...       ..||..|.|
Worm   798 ITNKTPQITARLDAMD-------VSEGTSTSQ 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	23/81 (28%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	23/80 (29%)
sart-3	NP_502136.1	RRM_SF	681..761	CDD:418427	23/79 (29%)
		Lsm_interact	818..835	CDD:398843	2/5 (40%)
		TPR	209..494	CDD:223533
		RRM_SF	594..664	CDD:418427	25/90 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23236
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010