DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12288 and rbm-39

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_500025.1	Gene:	rbm-39 / 176922	WormBaseID:	WBGene00021921	Length:	580	Species:	Caenorhabditis elegans

Alignment Length:	385	Identity:	72/385 - (18%)
Similarity:	139/385 - (36%)	Gaps:	89/385 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KSKTKPKKKTVKVPKDEVKAAVQESPKKLSAKDLAKIEKKKAKKQAQKLKKQQNKLAP---KEIK 93
            :|::|.::.|.:           .||.:  .:..::...:.|.::..:.:.:..:.:|   ::.:
Worm    69 RSRSKDRRTTRR-----------RSPSR--ERRRSRSRDRGAPRRRSRTRSRDRRRSPPRRRDRR 120

  Fly    94 TEPE----AQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEA 154
            |.|.    .:....|:....|:.:..|....:..||   :.|.:..|..:|:.
Worm   121 TPPRRSPGRRSPPRSRLPGPERRDVMPFNPRHSPPK---NAKLELTAEERDQR------------ 170

  Fly   155 STVFVGNLPINTKRVQLVKLFQPYGLVQSIRL----RTAGGKQLFKHKQRKVAGSLNAYVVLEKP 215
             |:.:..:..:|:...|.:.|...|.|:.:|:    ||...|.:             .||.....
Worm   171 -TLLIMQIARDTRPRDLEEFFSAVGAVRDVRIITDSRTGRSKGI-------------CYVEFWDE 221

  Fly   216 EIAQQALALNGSEFKENHL----------RVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYS 270
            |.....|||||.......|          |...:|:|...|..   .|.:|.... :.|.:|...
Worm   222 ESVPLGLALNGQRLMGAPLQIQRTCAERNRAANSSVASTLGFV---APGNKGPTH-VLVENLHPK 282

  Fly   271 ATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINVERY 334
            ..|:.:|:||.|.|.|:.|....|.::..:|.|.:.|:..|....:.| ||...|..|.|.:
Worm   283 IDEKMIRDIFESFGRIEKIDLEVDSNRENRGFATITFRNADDAQKSCEQLNNFELAGRCIRL--- 344

  Fly   335 QVKKLGAKQVRDAAAASAASKTSSKTKAKNQN----------SAGAKKRLDKKKGKENGS 384
                    .::..:.|.|..|..:....::.:          .||.:::|..|..:..||
Worm   345 --------SIKQESQAPAVKKEEASIHQRSLDDVGDRQGFSLGAGGRQQLMAKLAQGTGS 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	20/95 (21%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/71 (30%)
rbm-39	NP_500025.1	RRM1_RBM39_like	171..243	CDD:240729	19/84 (23%)
		RRM_SF	276..345	CDD:302621	21/79 (27%)
		RBM39linker	367..438	CDD:292157	6/30 (20%)
		RRM3_RBM39_like	421..505	CDD:240731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910