DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and tiar-2

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_496718.1	Gene:	tiar-2 / 174909	WormBaseID:	WBGene00012904	Length:	434	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	62/258 - (24%)
Similarity:	104/258 - (40%)	Gaps:	51/258 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 KANANNKDEEGVKRIRNPAEEASTVFVGNL-PINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFK 196
            :.:|...:.||. ::.:.:|:..|:||.|| |..|... |..||...|.|...::       :|:
Worm    19 RVHARIAEREGF-QLASGSEDPRTLFVANLDPAITDEF-LATLFNQIGAVMKAKI-------IFE 74

  Fly   197 HKQRKVAGSLNAYVVLEKPEIAQQALAL---NGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDA 258
                   |..:.|..:|..:..|..|||   ||.|..|..:.||.|....:.|:.:.|..:.:..
Worm    75 -------GLNDPYAFVEFSDHNQATLALQSHNGRELLEKEMHVTWAFEPREPGENRSKPETSRHF 132

  Fly   259 KRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDG--DKGCKGVAYVCF-QKPDAVGLALELN 320
            .  :|||.|.......:|||.|...||:...:.::|.  :|| ||..:|.: ::.||.....|:|
Worm   133 H--VFVGDLCSEIDSTKLREAFVKFGEVSEAKIIRDNNTNKG-KGYGFVSYPRREDAERAIDEMN 194

  Fly   321 QTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENG 383
            ...|..|.|                         :|:..|:..:::......|.|::.|...|
Worm   195 GAWLGRRTI-------------------------RTNWATRKPDEDGERGGDRGDRRGGGGGG 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	24/85 (28%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	23/73 (32%)
tiar-2	NP_496718.1	RRM	36..321	CDD:223796	59/240 (25%)
		RRM_SF	42..113	CDD:302621	25/85 (29%)
		RRM_SF	133..207	CDD:302621	24/101 (24%)
		RRM3_TIA1_like	256..326	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910