DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and tiar-1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_495121.1	Gene:	tiar-1 / 173967	WormBaseID:	WBGene00015943	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	219	Identity:	54/219 - (24%)
Similarity:	91/219 - (41%)	Gaps:	30/219 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 AKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFK 196
            |:.::...:.||. .:.|.::|..|::||||........:..||...|.|...       |.:|.
Worm    24 ARMHSKLAEREGF-HLGNGSDEPRTLYVGNLDSTVTEDFIATLFNQIGSVTKT-------KVIFD 80

  Fly   197 HKQRKVAGSLNAYVVLEKPEIAQQALAL---NGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDA 258
                   ||.:.|..:|..:..|.:.||   |.....:..::|   :.|.:.||    |.|..|.
Worm    81 -------GSNDPYAFVEFSDHGQASQALQTMNKRLLLDREMKV---NWAVEPGQ----QQSKIDT 131

  Fly   259 KR--TIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQD-GDKGCKGVAYVCFQKPDAVGLALE-L 319
            .|  .:|||.|......::|||.|...|::...:.::| .....||..:|.:.|.:....|:| :
Worm   132 TRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQM 196

  Fly   320 NQTLLDDRPINVERYQVKKLGAKQ 343
            |...|..|.|.. .:..:|.|.::
Worm   197 NGQWLGRRTIRT-NWATRKPGDQE 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	19/84 (23%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	20/72 (28%)
tiar-1	NP_495121.1	PABP-1234	47..>302	CDD:130689	49/195 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910