DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and rnp-6

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_491176.1	Gene:	rnp-6 / 171922	WormBaseID:	WBGene00004389	Length:	749	Species:	Caenorhabditis elegans

Alignment Length:	407	Identity:	83/407 - (20%)
Similarity:	142/407 - (34%)	Gaps:	110/407 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 KKQAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANN 138
            ||.|||:....:||:.|                 :|:.::.....|.:...|..:.::.|....|
Worm    40 KKDAQKIGLGLSKLSSK-----------------RKDDIQMAKKYAMDISIKQILLRQQKQQQEN 87

  Fly   139 KDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLR---TAGGKQLFKHKQR 200
            :..:  :.........|.::||::....:...|.:.|.|:|.::||.:.   ..|..:.|
Worm    88 QQRQ--QMYSQALSIMSRIYVGSISFEIREDMLRRAFDPFGPIKSINMSWDPATGHHKTF----- 145

  Fly   201 KVAGSLNAYVVLEKPE---IAQQAL---ALNGSEFKENHLRVTPASMAEKFGQAKDKQP----SD 255
                   |:|..|.||   :||:::   .|.|...|.|.:......:.:...||   ||    ..
Worm   146 -------AFVEYEVPEAALLAQESMNGQMLGGRNLKVNSMMFQEMRLPQNMPQA---QPIIDMVQ 200

  Fly   256 KDAKR--TIFVGSLKYSATEEQLREIFSSCGEIDYIRC---LQDGDKGCKGVAYV---------- 305
            ||||:  .::|.|:....:|..|:.:|.:.|||  ::|   .....:|.:|..|:
Worm   201 KDAKKYFRVYVSSVHPDLSETDLKSVFEAFGEI--VKCQLARAPTGRGHRGFGYLEFNNLTSQSE 263

  Fly   306 -------------------CFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAAS 351
                               |...|||:        |.|....::.....|....|.......||.
Worm   264 AIAGMNMFDLGGQYLRVGKCVTPPDAL--------TYLQPASVSAIPASVSVACAAITAKVMAAE 320

  Fly   352 AASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLKKEGAPTGQKKKSEYRGVKVDGIKKA--KKP 414
            ||:.:|.||.:::                 .||.....||..|...:....:..|...||  ..|
Worm   321 AAAGSSPKTPSES-----------------GGSRAASPAPRAQSPATPSSSLPTDIENKAVISSP 368

  Fly   415 KKKSNDQQTALAKKIAP 431
            ||:..:.:.......||
Worm   369 KKEPEEIEVPPLPPSAP 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	22/90 (24%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	18/102 (18%)
rnp-6	NP_491176.1	half-pint	5..749	CDD:130706	83/407 (20%)
		RRM1_PUF60	102..177	CDD:240816	21/86 (24%)
		RRM2_PUF60	207..283	CDD:240817	12/77 (16%)
		RRM_SF	657..748	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910