DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and Hnrnpa1

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001034218.1	Gene:	Hnrnpa1 / 15382	MGIID:	104820	Length:	373	Species:	Mus musculus

Alignment Length:	211	Identity:	52/211 - (24%)
Similarity:	86/211 - (40%)	Gaps:	26/211 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 EEASTVFVGNLPINTKRVQLVKLFQPYG-LVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEKP 215
            |:...:|:|.|...|....|...|:.:| |...:.:|....|       |........|..:|:.
Mouse    11 EQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTK-------RSRGFGFVTYATVEEV 68

  Fly   216 EIAQQALALNGSEFKENHLRVTPASMAEKFGQAKDKQ-PSDKDAKRTIFVGSLKYSATEEQLREI 279
            :     .|:|....|.:...|.|.....:    :|.| |......:.||||.:|....|..||:.
Mouse    69 D-----AAMNARPHKVDGRVVEPKRAVSR----EDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDY 124

  Fly   280 FSSCGEIDYIRCLQDGDKGCK-GVAYVCFQKPDAVG-LALELNQTLLDDRPINVERYQVKKLGAK 342
            |...|:|:.|..:.|...|.| |.|:|.|...|:|. :.::...|      :|....:|:|..:|
Mouse   125 FEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHT------VNGHNCEVRKALSK 183

  Fly   343 QVRDAAAASAASKTSS 358
            |...:|::|...::.|
Mouse   184 QEMASASSSQRGRSGS 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	16/82 (20%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	23/72 (32%)
Hnrnpa1	NP_001034218.1	RRM1_hnRNPA1	12..92	CDD:241205	18/91 (20%)
		RRM2_hnRNPA1	105..181	CDD:241024	25/81 (31%)
		HnRNPA1	310..345	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910