DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and AgaP_AGAP001883

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_321180.5	Gene:	AgaP_AGAP001883 / 1281239	VectorBaseID:	AGAP001883	Length:	396	Species:	Anopheles gambiae

Alignment Length:	312	Identity:	73/312 - (23%)
Similarity:	123/312 - (39%)	Gaps:	59/312 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 DEVKAAVQESPKKLSAKDLAKIEKKKAKKQAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEK 111
            ::|.||||         ||.|.::::.::|.|:.::||.:
Mosquito     3 NKVLAAVQ---------DLQKQQQQQQQQQQQQQQQQQQQ------------------------- 33

  Fly   112 VEKEPTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQ 176
             :::.....|....|...:..:..|......|.:...|  ...:.:.|..||......::..||.
Mosquito    34 -QQQQQNGANGGGGGGGGEAGQTVAGGAAGGGGQSSDN--NSRTNLIVNYLPQTMTEEEIRSLFS 95

  Fly   177 PYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQAL-ALNGSEFKENHLRVTPAS 240
            ..|.|:|::|  ...|.:....|.|.......:|...:|:.|:||: .|||...:...|:|:.|
Mosquito    96 SVGEVESVKL--VRDKNVIYPGQPKGQSLGYGFVNYHRPQDAEQAVNVLNGLRLQNKVLKVSFA- 157

  Fly   241 MAEKFGQAKDKQPSDKDAK-RTIFVGSLKYSATEEQLREIFSSCGEIDYIRCL-QDGDKGCKGVA 303
                       :||.:..| ..:::..|..:.|:|:|..||...|||...|.| |||:...|||.
Mosquito   158 -----------RPSSEGIKGANLYISGLPKTITQEELETIFRPYGEIITSRVLIQDGNDKPKGVG 211

  Fly   304 YVCF-QKPDAVGLALELNQT----LLDDRPINVERYQVKKLGAKQVRDAAAA 350
            ::.| |:.:|......||.|    |.|...:.......:...||.|:.|..|
Mosquito   212 FIRFDQRKEAERAIQALNGTTPKGLTDPITVKFSNTPGQNAAAKVVQPALPA 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/82 (26%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	25/76 (33%)
AgaP_AGAP001883	XP_321180.5	ELAV_HUD_SF	71..396	CDD:273741	56/207 (27%)
		RRM1_Hu	73..157	CDD:241094	22/85 (26%)
		RRM2_Hu	167..245	CDD:241096	25/77 (32%)
		RRM3_Hu	314..391	CDD:240823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55893
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920