DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and AgaP_AGAP008433

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_317010.3	Gene:	AgaP_AGAP008433 / 1277542	VectorBaseID:	AGAP008433	Length:	526	Species:	Anopheles gambiae

Alignment Length:	354	Identity:	93/354 - (26%)
Similarity:	143/354 - (40%)	Gaps:	63/354 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KESEKAELKPIKKEPGVVEDGKVTKKSKTKPKKKTVKVPKDEVKAAVQESP-KKLSAKDLAKIEK 70
            ::.|||..|.....||...| |..::||.:.|.:               || ::..:||.:| ||
Mosquito    37 RDGEKASKKHRSGSPGRNRD-KERRRSKDRSKSR---------------SPARRDRSKDRSK-EK 84

  Fly    71 KKAKKQAQKLKKQQNKLAPKEIKTEP-EAQVKVESKATKKEKVEKEPTTAPN---EKPKGKVSKK 131
            .:.|....:          :|:..|. .::.:|:.:...:|:..:..:.:.:   ...:|:.|..
Mosquito    85 DRGKSDHHR----------REVVVEKRRSRDRVDHRRRSRERDYRRRSRSRDGGRGMGRGRRSMS 139

  Fly   132 AKA-NANNKDEEGVKRIRNPAEE-------ASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRT 188
            .|. ....:...|..|.|:|.||       |.|||...|........|.:.|...|.|:.:||.|
Mosquito   140 PKPYRGRGRGGSGYYRDRSPLEEMSQEDRDARTVFCMQLSQRIHARDLEEFFSSVGKVRDVRLIT 204

  Fly   189 AGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSE-----FKENHLRVTPASMAEKFGQA 248
            ....:.||.         .||:..:.||....||.|:|.:     ....|.:.....||.:...|
Mosquito   205 CNKTKRFKG---------IAYIEFKDPESVALALGLSGQKLLGIPISVQHTQAEKNRMASQPPVA 260

  Fly   249 KDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVCFQKPDA 312
            ..|.||   ....::||||.::.||:.|..||...|:||.|:.:.|.|.| .||..::.|...|.
Mosquito   261 PPKNPS---GPMRLYVGSLHFNITEDMLNGIFEPFGKIDNIQLIMDADTGRSKGYGFITFHNADD 322

  Fly   313 VGLALE-LNQTLLDDRPINV----ERYQV 336
            ...||| ||...|..||:.|    ||..|
Mosquito   323 AKKALEQLNGFELAGRPMKVGNVTERLDV 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	22/86 (26%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	29/76 (38%)
AgaP_AGAP008433	XP_317010.3	PRP38_assoc	<40..109	CDD:289628	22/95 (23%)
		SF-CC1	53..511	CDD:273721	87/338 (26%)
		RRM1_RBM39_like	172..244	CDD:240729	21/80 (26%)
		RRM2_RBM23_RBM39	271..343	CDD:240730	28/71 (39%)
		RBM39linker	360..436	CDD:292157
		RRM3_RBM39_like	418..502	CDD:240731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910