DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12288 and Hnrnpm

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001103381.1	Gene:	Hnrnpm / 116655	RGDID:	620369	Length:	729	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	69/288 - (23%)
Similarity:	108/288 - (37%)	Gaps:	69/288 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EAQVKVESKATKKEKVEKEP-TTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEAST---- 156
            ||..:|.:...|.|:....| ..:.|..|..|..::...|...| |:.:||..|..|..:.
  Rat     6 EAAAEVAATEPKMEEESGAPCVPSGNGAPVPKGEERPTQNEKRK-EKNIKRGGNRFEPYANPTKR 69

  Fly   157 --VFVGNLPINTKRVQLVKLF-QPYGLVQSIR-LRTAGGKQL------FKHKQ--RKVAGSLNAY 209
              .|:.|:|.:.|...|..|. :..|.|..:. |..|.||..      ||.::  :|.|..||.:
  Rat    70 YRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKH 134

  Fly   210 VVLEKP---------EIAQQAL-------------------------ALNGSEFKENHLRVTPAS 240
            .:..:|         |.|::|:                         .||......   .:..|.
  Rat   135 SLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPN---EIIHAL 196

  Fly   241 MAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYV 305
            .|.:.|.             |:||.:|.|....::|:|:||..|.:.....|:|.|...:|:..|
  Rat   197 QAGRLGS-------------TVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTV 248

  Fly   306 CF-QKPDAVGLALELNQTLLDDRPINVE 332
            .| |..:||......|..||.|||::|:
  Rat   249 TFEQSIEAVQAISMFNGQLLFDRPMHVK 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	24/131 (18%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	25/71 (35%)
Hnrnpm	NP_001103381.1	HnRNP_M	40..69	CDD:402915	7/29 (24%)
		RRM1_hnRNPM	71..146	CDD:410058	19/74 (26%)
		RRM2_hnRNPM	203..278	CDD:410060	26/87 (30%)
		antiphage_ZorA_3	<413..552	CDD:411477
		RRM3_hnRNPM	653..729	CDD:410062
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910