DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and AgaP_AGAP013051

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_003436593.1	Gene:	AgaP_AGAP013051 / 11176155	VectorBaseID:	AGAP013051	Length:	420	Species:	Anopheles gambiae

Alignment Length:	306	Identity:	59/306 - (19%)
Similarity:	101/306 - (33%)	Gaps:	99/306 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 TVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQ 220
            ::.|.|:..:|...||.:.|:.:|.:..|.:.|.|                .|||........|.
Mosquito   122 SIMVRNIRDDTTDWQLYEAFRRFGKIYGILIPTHG----------------TAYVGFYYEAETQC 170

  Fly   221 ALALNGSEFKENHLRV------TPASM------------------------AEKFGQAKDK--QP 253
            ||.:|.:.|..|.:||      .|...                        .|:|..|.|:  ..
Mosquito   171 ALEMNNNMFNGNRMRVEMLRRNLPLQQIDIFDITKNEVRLLRDMLLEVDEKLEQFYSAYDEAFNY 235

  Fly   254 SDKDAK--------------------------------------RTIFVGS-----------LKY 269
            |.||.:                                      |.|..||           :..
Mosquito   236 SSKDYRRWKRKRRRVTPLLSDSSSSSESSSSSVSEISNRSATEVRRILCGSNEENRCLGIFGMNP 300

  Fly   270 SATEEQLREIFSSCGEIDYIRCLQDGDKG-CKGVAYVCFQ-KPDAVGLALELNQTLLDDRPINVE 332
            ..||:.|.::||..|.:..|:.:.||... .:|.:::.|: ..||.....:||.|:|:.|.:.|:
Mosquito   301 DTTEKTLMKLFSRYGHVKDIKLIYDGKTNVSRGYSFIYFKHASDARRAQRKLNGTMLEGRKVRVD 365

  Fly   333 RYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKK 378
            ..:.|....:..|....:...:.||:......::.|...|:..|::
Mosquito   366 FSRSKPHEPRADRRKRVSPTVASTSADRCCHRRHGATHHKKRKKRR 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	21/86 (24%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	21/83 (25%)
AgaP_AGAP013051	XP_003436593.1	RRM	<35..163	CDD:223796	13/56 (23%)
		RRM	38..>93	CDD:214636
		RRM_SF	123..187	CDD:240668	20/79 (25%)
		RRM	<286..>381	CDD:223796	22/94 (23%)
		RRM_SF	292..367	CDD:302621	19/74 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910