Protein Alignment CG12288 and SRSF10

DIOPT Version :10

• Sequence 1: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Sequence 2: NP_473357.1
• Gene: SRSF10 / 10772
• HGNCID: 16713
• Length: 262
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 53/283 - (18%)
• Similarity: 106/283 - (37%)
• Gaps: 54/283 - (19%)

  Fly   155 STVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQ 219
            :::||.|:..:|:...|.:.|..||.:..:.:..    ..:..:.|..     |||..|....|:
Human    10 TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPL----DFYTRRPRGF-----AYVQFEDVRDAE 65

  Fly   220 QALALNGSEFKENHLR--VTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSS 282
            .||        .|..|  :....:..:|.|...|.|:...||               :.|.::||
Human    66 DAL--------HNLDRKWICGRQIEIQFAQGDRKTPNQMKAK---------------EGRNVYSS 107

  Fly   283 CGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALELN----QTLLDDRPINVERYQVKKLGAKQ 343
            ....||.|..:...:.        :::..:...:.:.|    .:..:.||....|.........:
Human   108 SRYDDYDRYRRSRSRS--------YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR 164

  Fly   344 VRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLKKEGAPTGQKKKSEYR-GVKVDG 407
            .:....:.:.||::|::::|:|    .||.:..|....:.|..|....:....|:.|: |.:.:.
Human   165 FKHRNRSFSRSKSNSRSRSKSQ----PKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK 225

  Fly   408 IKKAKKP---KKKSNDQQTALAK 427
            ..:.|:|   |.:|..|..:.:|
Human   226 ESRKKEPPRSKSQSRSQSRSRSK 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	18/82 (22%)
		RRM_SF	261..332	CDD:473069	9/74 (12%)
SRSF10	NP_473357.1	RRM_SF	5..99	CDD:473069	22/105 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..262		23/145 (16%)