DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12288 and otogl2

DIOPT Version :9

Sequence 1:	NP_609822.1	Gene:	CG12288 / 35027	FlyBaseID:	FBgn0032620	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	XP_031761380.1	Gene:	otogl2 / 101733689	XenbaseID:	XB-GENE-6035211	Length:	3475	Species:	Xenopus tropicalis

Alignment Length:	446	Identity:	84/446 - (18%)
Similarity:	143/446 - (32%)	Gaps:	110/446 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KTPKAKESEKAELKPIKKEPGVVEDGKVTKKSKTKPKKKTVKVPKDEVKAAVQESPKKL-SAKDL 65
            |..|..::.|:..:..:.|.|.::|.......|.   |:.|...:|||.....:.|..: |::..
Frog    30 KIYKNGDTVKSNCQICECENGKIKDCARDVNCKI---KRAVTPEQDEVPIVYDDDPSVIESSEGK 91

  Fly    66 AKIEKKKAKKQAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKG--KV 128
            ..:..|:|.....|......|.:.....|:       |.|...|..|:.:.......:.||  ..
Frog    92 GNVRAKRAAVGVNKKNSAATKFSLGITGTD-------EDKEFLKTNVKNDKVNTNQNQGKGHDDS 149

  Fly   129 SKKAKANANNKDEEGVKRIRNPAEE----ASTVFVGNL---PINTKRVQLVKLFQPYGLVQSIRL 186
            .|.:|.|:..|.:|..|:....:.|    .|....||:   .:||.:.|
Frog   150 RKDSKENSQEKGQENNKKFSKDSSEEKDDGSKEKWGNVKNDKVNTNQNQ---------------- 198

  Fly   187 RTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFKEN-------HLRVTPASMAEK 244
                ||   .|...:.....|:.   ||.:...:..:.:.||.|:|       ..:......::.
Frog   199 ----GK---GHDDSRKDSKDNSQ---EKGQQNNKRFSKDSSEEKDNASKEKSTFKKTYSVQTSQN 253

  Fly   245 FGQAKDKQPSD-KDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQ 308
            .|:..|...|: |:.|:..........::||:                 .||.|
Frog   254 QGKGHDDSSSESKENKKGQNKNGFSKDSSEEK-----------------DDGSK----------- 290

  Fly   309 KPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQV-RDAAAASAASKTSSKTKAKNQNSAGAKK 372
                                   |:...||..:.|. ::.......|.:.||...|.||..|..|
Frog   291 -----------------------EKSAFKKTYSVQTSQNQGKGHDDSSSESKENKKGQNKNGFSK 332

  Fly   373 RLDKKKGKENGSLKKEGAPTGQKKKSEYRGVKVDGIKKAKKPKKKSNDQQTALAKK 428
              |..:.|::||.:|.|.....|.|....  |.:....:.|..|::.|:|.....|
Frog   333 --DSSEEKDDGSKEKSGHGKNDKNKPNIN--KGNDHDDSSKESKENTDRQKGQKNK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12288	NP_609822.1	RRM1_RBM34	155..237	CDD:240840	16/91 (18%)
CG12288	NP_609822.1	RRM_SF	261..332	CDD:302621	5/70 (7%)
otogl2	XP_031761380.1	elast_bind_EbpS	121..442	CDD:411220	65/352 (18%)
		VWD	520..683	CDD:214566
		TIL	894..953	CDD:396409
		VWD	983..1134	CDD:413350
		C8	1171..1238	CDD:400886
		PHA03247	<2898..3171	CDD:223021
		GHB_like	3354..3436	CDD:419725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910