Protein Alignment CG6012 and IFA38

DIOPT Version :10

• Sequence 1: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_009717.1
• Gene: IFA38 / 852456
• SGDID: S000000363
• Length: 347
• Species: Saccharomyces cerevisiae
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 143/275 - (52%)
• Gaps: 29/275 - (10%)

  Fly    49 GDWAAVTGASDGIGKEYAKELARQNINVVLIARTEEKLQAVAKEIADCGAGVQTKIVIADFTKGS 113
            |.:.|:||||||||||:|:::|::..|:|||:||:.||:|:.||:.| ...|..||:..|..:..
Yeast    62 GKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELED-QHHVVVKILAIDIAEDK 125

  Fly   114 QV-YEHIEKETANIPISILVNNVG--IATPKSLLKYNQEETQNIIDTNVVAVSQLSRIFFQRM-- 173
            :. ||.|::..|.:||::||||||  .:.|...|:..::|.:|||..|..|...:::|...::
Yeast   126 ESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTATLLITQIIAPKIVE 190

  Fly   174 ------KASKLKGAIVNVGSGTELQPLPNGAYYAASKAYTRSLTLALYHEAKPYGIHVQMLSPNF 232
                  |.|..:|.|:.:||...|.|.|..|.|:.||::.:..:.:|..|.....|.|:::. ::
Yeast   191 TVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELII-SY 254

  Fly   233 VVTKINSYSRQIMKGGLLIPSASAYAKSAVNQLRDEVDETPGY-----LWHHV--QNAVATAFTW 290
            :||   |...:|.:..|:||:...:.||.:..:.........|     .|.|.  |..:...|.
Yeast   255 LVT---SSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFG- 315

  Fly   291 RVRTYVACKLFNKIS 305
                 |..|:.|.|:
Yeast   316 -----VYSKIVNSIN 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	82/264 (31%)
IFA38	NP_009717.1	17beta-HSD1_like_SDR_c	62..310	CDD:187614	81/252 (32%)