Protein Alignment CG6012 and HSD17B3

DIOPT Version :9

• Sequence 1: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_000188.1
• Gene: HSD17B3 / 3293
• HGNCID: 5212
• Length: 310
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 97/279 - (34%)
• Similarity: 156/279 - (55%)
• Gaps: 13/279 - (4%)

  Fly     5 LSAFLTFVGVYALSSYLYEQLRTPYKLIKIRYFSGTRPTLKERFGDWAAVTGASDGIGKEYAKEL 69
            |..|....|:....:.|.:.:|.. :.:.:.|:.....:.....|.||.:|||.|||||.|:.||
Human     5 LEQFFILTGLLVCLACLAKCVRFS-RCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFEL 68

  Fly    70 ARQNINVVLIARTEEKLQAVAKEIADCGAGVQTKIVIADFTKGSQVYEHIEKETANIPISILVNN 134
            |::.:|||||:||.|||:|:|.|| :...|...||:.||||| ..:||||:::.|.:.|.|||||
Human    69 AKRGLNVVLISRTLEKLEAIATEI-ERTTGRSVKIIQADFTK-DDIYEHIKEKLAGLEIGILVNN 131

  Fly   135 VGI---ATPKSLLKYNQEETQNIIDTNVVAVSQLSRIFFQRMKASKLKGAIVNVGSGTELQPLPN 196
            ||:   ..|...|. ..:|.|::|..|:.:|.:::::..:.|: |:.||.|:|:.||..|.|.|.
Human   132 VGMLPNLLPSHFLN-APDEIQSLIHCNITSVVKMTQLILKHME-SRQKGLILNISSGIALFPWPL 194

  Fly   197 GAYYAASKAYTRSLTLALYHEAKPYGIHVQMLSPNFVVTKINSYSRQIMKGGLLIPSASAYAKSA 261
            .:.|:||||:..:.:.||..|.|...:.:|:|:|..|.|.:..|    :...::..:|..:.|.:
Human   195 YSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKY----LNTNVITKTADEFVKES 255

  Fly   262 VNQLRDEVDETPGYLWHHV 280
            :|.:... .||.|.|.|.:
Human   256 LNYVTIG-GETCGCLAHEI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	91/235 (39%)
		adh_short	51..243	CDD:278532	82/194 (42%)
HSD17B3	NP_000188.1	17beta-HSD1_like_SDR_c	48..284	CDD:187614	91/235 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0300
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2265
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D584062at33208
OrthoFinder	1	1.000	-	-		FOG0000465
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770