Protein Alignment CG6012 and Ldsdh1

DIOPT Version :10

• Sequence 1: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 248
• Identity: 62/248 - (25%)
• Similarity: 103/248 - (41%)
• Gaps: 34/248 - (13%)

  Fly    42 PTLKERFGDWAAVTGASDGIGKEYAKELARQNINVVLIARTEEKLQAVAKEIADCGAGVQTKIVI 106
            |.|.:..|....:||...|:|||.|.:.|:....::.....|:......|||.:.|.  :....:
  Fly    51 PPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGG--KAFGYV 113

  Fly   107 ADFTKGSQVYE---HIEKETANIPISILVNNVGIATPKSLLKYNQEETQNIIDTNVVAVSQLSRI 168
            .:.||..::.|   .:.||...  |.::|||.||.....||::.:.|.:.:.:.||::...:.:.
  Fly   114 CNVTKREELIELAQKVRKEHGF--IHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWIIQA 176

  Fly   169 FFQRMKASKLKGAIVNVGSGTELQPLPNGAYYAASKAYTRSLTLALYHEAKPYGIHVQMLSP--N 231
            |...| ..:.:|:||.:.|...|..|.|...|..:|...|....||..|       ::..:|  |
  Fly   177 FLPDM-IERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEE-------LRQKNPQNN 233

  Fly   232 FVVTKINSYSRQIMKGGL-------------LIPSASAYAKSAVNQLRDEVDE 271
            ..:|.|..|   ::..||             ||| |...|.|.:...|..::|
  Fly   234 VKLTTIYPY---MIDTGLCKNPRYRFPNLFKLIP-ADVAAGSIIEAQRQGLEE 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	60/241 (25%)
Ldsdh1	NP_572436.1	Rossmann-fold NAD(P)(+)-binding proteins	60..287	CDD:473865	59/239 (25%)