Protein Alignment CG6012 and dhs-27

DIOPT Version :10

• Sequence 1: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_508591.3
• Gene: dhs-27 / 180632
• WormBaseID: WBGene00000990
• Length: 320
• Species: Caenorhabditis elegans
• Alignment Length: 294
• Identity: 84/294 - (28%)
• Similarity: 138/294 - (46%)
• Gaps: 14/294 - (4%)

  Fly     5 LSAFLTFVGVYALSSYL-YEQLRTPYKLIK--IRYFSGTRPTLKERFGDWAAVTGASDGIGKEYA 66
            :|..|.....:|::||: ...|:..|.:.|  :.:|...:..|......|..:||.:|||||.|.
 Worm     1 MSGALWSAAQFAVTSYVCVRVLKFLYIMCKSVLVHFITPKHDLDYLKDTWTVITGGTDGIGKAYI 65

  Fly    67 KELARQN--INVVLIARTEEKLQAVAKEIADCGAGVQTKIVIADFTKGSQVYEHIEKETANIPIS 129
            :||.:..  ....||.|..:||....||:.: ..|.:....:.||.|..  ...:.|:...:.:.
 Worm    66 EELCKTRGLKKFYLIGRNIDKLNNTKKELVE-QHGCEVMCHVHDFEKDD--LSALPKDLETLDVG 127

  Fly   130 ILVNNVGIATPK---SLLKYNQEETQNIIDTNVVAVSQLSRIFFQRMKASKLKGAIVNVGSGTEL 191
            ||:|..||| |.   :|.:..:.....|:..|:::..:::.:....| ..|.:|.|||:.|.|..
 Worm   128 ILINCAGIA-PHIIGTLTELPEGLASKILRVNLMSAVKMTEMILPNM-VKKKRGIIVNISSMTGW 190

  Fly   192 QPLPNGAYYAASKAYTRSLTLALYHEAKPYGIHVQMLSPNFVVTKINSYSRQIMKGGLLIPSASA 256
            :|||..:.|.||||.....:.:|..|.:..||.||.|.|..|.||:.||..: ....:.:.:...
 Worm   191 RPLPYLSSYPASKAALSFFSDSLSDEYRGTGIRVQCLIPMLVATKVASYEAE-EANNIFVVTPEN 254

  Fly   257 YAKSAVNQLRDEVDETPGYLWHHVQNAVATAFTW 290
            :||.||..:....:.|.|.:.|.||.|:.|.|::
 Worm   255 FAKQAVRIIGTNWEITTGCVQHDVQVALGTLFSF 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	74/247 (30%)
dhs-27	NP_508591.3	17beta-HSD1_like_SDR_c	48..294	CDD:187614	74/247 (30%)