Protein Alignment Nepl9 and Nep5

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_733186.2
• Gene: Nep5 / 43255
• FlyBaseID: FBgn0039478
• Length: 882
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 143/820 - (17%)
• Similarity: 252/820 - (30%)
• Gaps: 308/820 - (37%)

  Fly    53 LVKIKNDSMDPCDDFYAHACGNF-------------DQTKEENSD------DFLPPYLYNKQDRM 98
            |:...::..|||:|||...||.:             |..:|..:.      :||         |.
  Fly   142 LIYAMDEQTDPCEDFYQFTCGRWANEHPRPDSVTSNDWFRERQAHIMRVVREFL---------RS 197

  Fly    99 NFFTAE---VGNFETIPGRLISQLYTECR------KREERNVFT----------PTRLT------ 138
            |...:|   ||..:|        :|..|.      ||:...:..          |:.|.
  Fly   198 NITKSEPEAVGKAKT--------MYRACMDTKLLDKRDLEPLINYLLRFGLPVLPSALNLTLGSG 254

  Fly   139 -----------SHWERMLDEIPFLARH---------------------------KEVLSSWPFLK 165
                       .:|   |..|..:.:|                           .|..|::||..
  Fly   255 SKYATEAANVKYNW---LQSIVSIKQHLTMDLIIGFDVFPDPFNRTINRIALGTPETDSAFPFNN 316

  Fly   166 HQWER--RRLYGQLNWIVLS-----------------AQLAAHGLPTLLHIYFALDTIYVSPMEE 211
            ....:  |:::.:..::..|                 |:..:.|:...||....:...|:..::
  Fly   317 DDSHKMLRKIHRKTIFMQNSDDEDDSEDDRESEEEEAAKQTSTGMTAYLHYVRKVIEKYLLYVD- 380

  Fly   212 LPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVL--CREMRGELPLVRSLSQNTRTNTSRPGEE 274
               |::...:::|.         ::.::...:||.  ..|.:.|       ::|....:..|.::
  Fly   381 ---PNVNQEEATLG---------ITELVKQGVRVARKVHEFKEE-------AENMTKPSKNPADD 426

  Fly   275 ---------QLLLDEN----TMDYFQQYFAALNFSEERLVGAR--------------KFPLDVEK 312
                     |...|:|    |:..:.:|...:      |.|.|              ....|:..
  Fly   427 IVYITLQDLQNQTDKNIAPKTLPIWVRYMELI------LKGTRHAGNIQMTQNLTIITSQADITY 485

  Fly   313 ITQAWEVLRHTETRIVYNYVMWQAREQLRYPDCYRVSEEFERLLHAEYWQWHVLRRHLSRE---- 373
            :....|.|..|....:.:|:.....|:|    ....|... ||||:||     :|..:..|
  Fly   486 LQNIVEYLDDTPASHIESYLFLSTIEEL----VLHTSSSM-RLLHSEY-----MRVAIGTEGSTP 540

  Fly   374 ------------VALA-SYQLHTTRFQKLRRSKLSR-----RDWYGHL-----WPASVEKKELQV 415
                        :.:| ||.|....|.|.:..|:.|     |..:..|     |..:..|:
  Fly   541 RSLYCANGVNSLLGMAVSYVLADADFTKEKLPKVERMLSDIRRSFDRLVKSTSWMDAATKR---- 601

  Fly   416 ARILQNHAE--NYL-------NITELNENYEGLKLEKNSFYANLLILRRAQLRHSF--------- 462
             :.:|..||  :::       |.:.||..|||.::..::...||:.....|:....
  Fly   602 -KTIQKSAEMKSFIGFPPWLRNASVLNAYYEGAEVNASTHLENLMDFVHWQMMDKLNEMDKPEPI 665

  Fly   463 ---VSPYVDEEDVNQPAYFLRHFLHFVLLSLHRPTYH----------------YYATHGLE---- 504
               .||    .:||....|..:.:...:..|..|.|.                :..|||.:
  Fly   666 GWATSP----SNVNAFHTFQSNAITVPIAILQYPFYDLGLEALNYGSIGTILGHELTHGFDDSGR 726

  Fly   505 ---------LWRESRLLLDTDGHYTAMDCLERQSFQHY--------DAKLAPIYRPLGSH----- 547
                     .|..:|.:   |.:....:|...|..:::        |.:|.     ||.:
  Fly   727 RFDRAGNMVEWWSNRTI---DEYVNRTECFVEQYSRYHLADIDEYIDGELT-----LGENIADNG 783

  Fly   548 EIAEIFQFYRSFQYSLTDYHFWLQG-ERFAFAETFVLDYFGL-----NPHRVLFYAVAQQLCNRQ 606
            .:.|.|..||.:...:......|.| |.::..:.|.:.:..|     .| ....||:....|..|
  Fly   784 GMREAFYAYRLYVKEVGRERSKLPGLEHYSHEQLFFISFGNLWCETYTP-AASRYALTDSHCPGQ 847

  Fly   607 TEIFAAQLNRGYM-NLPEFQEAFKCGAEKAMNPPS-RCMI 644
            ..:      ||.: |..||...|||.....|||.. :|.|
  Fly   848 MRL------RGVLSNSEEFARTFKCARGTPMNPDQPKCRI 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	140/807 (17%)
Nep5	NP_733186.2	M13	151..880	CDD:341056	140/808 (17%)