Protein Alignment Nepl9 and Nep4

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 870
• Identity: 159/870 - (18%)
• Similarity: 286/870 - (32%)
• Gaps: 287/870 - (32%)

  Fly    13 IQIVRSQNGEDSDSDTEVEMDSEVESGQFF-------SHLYKSNLQQLVKIKNDSMDPCDDFYAH 70
            |:|...:..|....:...|:.....:.|.|       ..:..:..:.:.:..::.:|||.|||.:
  Fly   219 IRIRERREAERHAEEASAEISEATAALQSFWNEEGTREGIRMTQAKTMKRYMDNKVDPCVDFYKY 283

  Fly    71 ACGNFD---------------QTKEENSDDFLPPYL-----------------------YNKQ-- 95
            ||||::               :...|:.|..|...|                       .|:|
  Fly   284 ACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGE 348

  Fly    96 -----DRMNFFTAEVGNFETIPGR-LISQL------YTECRKREERNVFTPTRLTSHWE------ 142
                 |:....|||......:..| |::::      ||...|| :|.:.||...|...|
  Fly   349 GEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKR-KRLIETPRERTKEEEAAPPVV 412

  Fly   143 ----RMLDE--------IP--FLARHKEV-------------------------------LSSWP 162
                :..|:        :|  ||..|::.                               |..||
  Fly   413 LPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWP 477

  Fly   163 FLKHQWERRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEE-----------LPC-- 214
            .|:.||..    ...||.||:|.|..:....|:..:...|   :...||           ||.
  Fly   478 VLESQWSE----SNFNWQVLAATLRRYNNDILIVQWVGAD---IKNSEENIVQFDQTGLGLPTRE 535

  Fly   215 ----PSIAD----FQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRP 271
                ||.|.    :|..:::|:    |::....:...||....:..|..|         ...:.|
  Fly   536 YFLQPSNAKYLQAYQRYMAEVM----HKMGASKADAQRVASELVAFETQL---------AGITAP 587

  Fly   272 GEEQL----LLDENTMDYFQ------QYFAALNFSEER-LVGARKFPL-DVEKITQAWEVLRHTE 324
            .|::|    |....|:|..|      ::.|.|...::| ::|..:..: .||.:::...:|..|:
  Fly   588 AEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYAVEYMSKLVTLLDETD 652

  Fly   325 TRIVYNYVMWQ-AREQLRYPDCYRVSEEFERLLHAEY----------WQWHVLRRHLSREVALAS 378
            .|.|.||:||: .|.::.     .|.:.|:.:..:.|          .:|.|....::..:.:|.
  Fly   653 PRTVSNYMMWRFVRHRIN-----NVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAV 712

  Fly   379 YQLHTTRF----------------QKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAENYL 427
            ..:..:|:                |:..|..|...||.........|:| :....:...:.:..|
  Fly   713 GSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEK-VNAMSLKIGYPDFIL 776

  Fly   428 NITELNENYEGLKLEKNSFYANLL--ILRRA----------------QLRHSFVSPYVDEE---- 470
            |.:|||..|.|:::....::.|.|  :|..|                |...:.|:.|....
  Fly   777 NPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKNQI 841

  Fly   471 ----DVNQPAYFLRHF---LHF----VLLSLHRPTYHYYATHGLELWRESRLLLDTDG--HYTAM 522
                .:.||.::.|||   |:|    |::.       :..|||.:   :...|.|.:|  |....
  Fly   842 MFPAGILQPPFYHRHFPKSLNFGGIGVVIG-------HELTHGFD---DKGRLFDRNGNIHKWWT 896

  Fly   523 DCLERQSFQHYDAKLAPIYRPLGSHEIAEI--------------------FQFYRSFQYSLTDYH 567
            |    .|.:.:|.:...|.....::.:.|:                    .|.:.::|..|.::.
  Fly   897 D----SSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHP 957

  Fly   568 FWLQGERFAFAETFVLDYFGLNPHRVLFYAVAQQLCN-RQTEIFAAQLNRG------------YM 619
            ..:..|        :|....:...::.|....|..|. .:.|....:||..            ..
  Fly   958 SEVSDE--------ILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLS 1014

  Fly   620 NLPEFQEAFKCGAEKAMNPPSRCMI 644
            |..:|...|.|.....|||..:|.:
  Fly  1015 NSVDFAREFNCPLGSPMNPQKKCSV 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	152/810 (19%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	152/812 (19%)