Protein Alignment Nepl9 and Nep2

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Alignment Length: 746
• Identity: 141/746 - (18%)
• Similarity: 248/746 - (33%)
• Gaps: 223/746 - (29%)

  Fly    53 LVKIKNDSMDPCDDFYAHACGNFDQTKEEN-SDDFLPPYLYN------KQDRMNFFTAEVGNFET 110
            |.|:|.: ::|||:||..|||.:  .:||| .||.:....::      ::...:..|||....|.
  Fly    97 LRKMKPE-VEPCDNFYEFACGTY--LEEENIPDDKVSISTFSVISDKLQEQLKDIITAERPETEP 158

  Fly   111 IPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLSSWPFLKHQ-------- 167
            ...||.:.||..|..:.......|..:|              |..|.|..||.:|..
  Fly   159 KHFRLPNLLYKACMNKTLIETLGPEPIT--------------RVAERLGGWPLIKGDSWNADDSW 209

  Fly   168 -WERR----RLYG-QLNWIV-----LSAQLAAHGLPTLLHIYFALDTIY-VSPMEELPCPSIADF 220
             |:.:    |..| .:::|:     :..|.:...|..|.....||...| |....|....:...:
  Fly   210 TWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKY 274

  Fly   221 QSSLSDVLEGRHHQVSR---IISHEMRVLCREMRGELPLVRSLSQ--NTRTNTSRPGEEQLLLD- 279
            ...:: ||.|.:..:::   ::|.|..:....:.......|:.|:  |.||    |.:.|....
  Fly   275 MVDIA-VLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRT----PAQLQAAYPY 334

  Fly   280 ENTMDYFQQYF-AALNFSEERLV--GARKFPLDVEKITQAWEVLRHTETRIVYNYVMWQAREQLR 341
            ...:||..... ..||.:|:.::  ....|..|:.|:      |..|..|::.||:.|:...
  Fly   335 VQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKL------LAKTPKRVIANYMFWRIHG--- 390

  Fly   342 YPDCYRV---SEEFERLLHAEYWQWHVLRRHLSREVALASYQLHTTRFQKL-------------- 389
                :.|   ||||.             :|.|....||:..|....|:::.
  Fly   391 ----FSVGFLSEEFR-------------KRQLQYATALSGRQEQEARWKECVDIATSSMDEVCED 438

  Fly   390 -------------------RRSKLSRRDWYGHL------------WPASVEKKELQVARILQNHA 423
                               :.||.:..:....:            |..:..|||.:    |:.|:
  Fly   439 DFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVNWMDAKTKKEAK----LKLHS 499

  Fly   424 --------ENYLNITELNENYEGLKLEKNSFYANLL-----------------ILRRAQLRH--- 460
                    :..|:..:|...|..|.::.:.::.:.|                 :.:...:||
  Fly   500 MATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPVNKTDWVRHARP 564

  Fly   461 SFVSPYVD--EEDVNQPAYFLR-HFLHFVLLSLHRPTYHYYATHGLELWRESRLLLDTDGHY--- 519
            :.|:.:..  |..:..||..|: ||     .:..||.|..:...|..:..|.....|..|..
  Fly   565 AIVNAFYSSLENSIQFPAGILQGHF-----FNAQRPKYMNFGAIGYVIGHEITHGFDDQGRQFDV 624

  Fly   520 --TAMDCLERQSFQHYDAKLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQGERFA----FA 578
              ...|.....:.:.|.||...|....|::.       .|:...:|...:  .|||..|    ..
  Fly   625 KGNLRDWWHPDTQKAYLAKAKCIIEQYGNYT-------ERATGLNLNGIN--TQGENIADNGGVK 680

  Fly   579 ETFV-----------------LDYFGLNPHRVLFYAVAQQLCNR-QTEIFAAQLNRG-------- 617
            |:::                 |||   .|.::.:.|..|..|.: :.|....::..|
  Fly   681 ESYIAYRRWAEKHGPEAKLPGLDY---TPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFR 742

  Fly   618 ----YMNLPEFQEAFKCGAEKAMNPPSRCMI 644
                ..|:.:|.:.|.|.....|||..:|.:
  Fly   743 VLGSLSNMKDFAKDFHCPEGSPMNPVQKCEV 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	11/22 (50%)
		GluZincin	<579..642	CDD:301352	17/92 (18%)
Nep2	NP_001246914.1	M13	104..772	CDD:189000	137/735 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910