Protein Alignment Nepl9 and Kel

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 730
• Identity: 138/730 - (18%)
• Similarity: 231/730 - (31%)
• Gaps: 235/730 - (32%)

  Fly    58 NDSMDPCDDFYAHAC-------GNFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIPGRL 115
            |.|..||.||::.||       .:|....|||..     .|:...:....:..|.|..:..
  Rat    75 NRSAAPCTDFFSFACEKANGTSNSFQALAEENKS-----RLWKLLEAPGSWHLESGEEKAF---- 130

  Fly   116 ISQLYTECRKREERNVFTPTRLTSHWERMLDEI------PFLARHKE-----VLSSWPFLKHQWE 169
              |.|..|..                   .|.|      |.:...||     :..:|.|......
  Rat   131 --QFYNSCMD-------------------TDAIEASGTGPLVQIIKELGGWNISGNWTFFDFNQN 174

  Fly   170 RRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPCPSIADFQSSLSDVLEGRHHQ 234
            .|.|..|..                   :|.....|:.|....|...|........|:|. :..|
  Rat   175 LRLLMSQYG-------------------HFPFFRAYLHPHPAPPHTPIIQIDQPEFDILL-QQDQ 219

  Fly   235 VSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTS-------------RPGEEQLLLDE----NT 282
            ..::.:..:|.....:.....|:.|..|..:.:.|             ||.::|...|:    .|
  Rat   220 EQKVYAQILREYVTYLNRLGTLLGSNPQEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVT 284

  Fly   283 MDYFQQ-------------YFAALNFSEERLVGARKFPLD-VEKITQAWE--VLRHTETRIVYNY 331
            :|..|:             .|..::.|..:.:  :...|| :..::|..|  :|.|:|  |:.:|
  Rat   285 IDALQEMAPAIDWLSCLQAIFTPMSLSPSQTL--QVHDLDYLRNMSQLVEEGLLNHSE--IIQSY 345

  Fly   332 VM---------------WQAREQL--------------RYPDCYRVSEE----FERLLHAEYWQW 363
            ::               .:||.:|              .||...:..|:    ||..|.|.:
  Rat   346 MILGLVDTLSPALATKFQEARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALF--- 407

  Fly   364 HVLRRHLSREVALASYQLHTTRFQKL------RRSKLSRRDWYGHLWPASVEKKE----LQVARI 418
              :.......:..|:.:|    |.::      |..|||        |.:...:||    |...::
  Rat   408 --VHEAFGPSIRSAAMEL----FAEIKDAVIVRLKKLS--------WISEETRKEALNKLTQLQV 458

  Fly   419 LQNHAENYLNITELNENYEGLKLEKNSFYANLLILRRAQLR--HSFVSPYVDEEDVNQP----AY 477
            .....:..|......:.|..::|..:...:.|..:|..|.|  .||:.|:........|    ||
  Rat   459 EMGAPKRALKTEMAKQEYSDIQLGPSFLQSFLSCVRSLQGRKVRSFLQPFPYHRWQKSPWSVSAY 523

  Fly   478 FL--RHFLHFVLLSLHRPTYH--------------YYATHGLELWRESRL-----LLDTDGHYTA 521
            :.  .|.:.|....|..|.:|              ..|...|.::.:..|     ..||.....|
  Rat   524 YSVPDHVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHIFFQFLLPGGCPACDTRALQEA 588

  Fly   522 MDCLERQSFQHYDAKLAPIYRPL-GSHEIAE----------IFQFYRSFQYSLTDYHFWLQGERF 575
            :.|||.:    |.|...|..... |||.:.|          .||.||.   .:|:    ..||
  Rat   589 LLCLEHR----YAAFPLPSMSSFNGSHTLLENAADIGGVAIAFQAYRK---RITE----RTGE-- 640

  Fly   576 AFAETFVLDYFGLNPHRVLFYAVAQQLCNRQTEIFA-----------AQLNRGYMNLPEFQEAFK 629
                 ..|....|:|:::.|.:.||.:|.   |:.:           .:::....|.|:|.:.|.
  Rat   641 -----LTLPNQELSPYQLFFRSYAQVMCR---ELISQDPQDTHSPPRLRVHGPLSNSPDFAKHFL 697

  Fly   630 CGAEKAMNPPSRCMI 644
            |.:...:||.:||.:
  Rat   698 CPSGSLLNPSTRCKL 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	10/28 (36%)
		GluZincin	<579..642	CDD:301352	15/73 (21%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	138/730 (19%)
		M13	78..711	CDD:189000	135/724 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000