Protein Alignment Nepl9 and Phex

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_037136.2
• Gene: Phex / 25512
• RGDID: 3323
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 747
• Identity: 135/747 - (18%)
• Similarity: 245/747 - (32%)
• Gaps: 244/747 - (32%)

  Fly    58 NDSMDPCDDFYAHACGNFDQTKEENSDDFLP-----PYLYNKQDRMNFFTAEVGNFETIPGRLIS 117
            |.|:|||::|:..||..:........|  :|     |:|.:..|.         ..:.:..:.:|
  Rat    71 NLSVDPCENFFRFACDGWISNNPIPED--MPSYGVYPWLRHNVDL---------KLKALLEKSVS 124

  Fly   118 Q------------LYTECRKREERNVFTPTRLTSHWERMLDEIPFL--ARHKEVLSSWPFLKHQ- 167
            :            ||:.|  ..|:.:           ...|..|.|  .||...  .||.|:..
  Rat   125 RRRDTEAVQKAKILYSSC--MNEKAI-----------EKADAKPLLHILRHSPF--RWPVLEANI 174

  Fly   168 -----WERR---------------------RLYG------------QLNWIVLSAQLAAHGLPTL 194
                 |..|                     |||.            :|:...||..:....|...
  Rat   175 GPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDFLDNT 239

  Fly   195 LH-------IY-FALDTIYV----SPMEELPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVLC 247
            ..       :| |.:||..:    |...|....|:...:..:::::....::.|..:.::|.:
  Rat   240 TEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNI-- 302

  Fly   248 REMRGELPLVRSLSQNTRTNTSR--PGEEQLLLDENTMDYFQQYFAALNFSEERLVGARKFPLDV 310
            .|:...:|....|....:...:|  |..:.:...||.:....|||..|    .|::||.:
  Rat   303 SELSAMIPQFDWLGYIKKVIDTRLYPHLKDIGPSENVVVRVPQYFKDL----FRILGAER----- 358

  Fly   311 EKITQAWEVLRHTETRIVYNYVMWQ----------AREQLRYPDCYRVSEEFERLLHAEYWQW-- 363
                          .:.:.||::|:          .|.|.|:.:..||.:....||.    ||
  Rat   359 --------------KKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLP----QWDK 405

  Fly   364 --HVLRRHLSREVALASYQLHTTRFQKLRRSKL----------------SRRDWYGHLWPASVEK 410
              :.:...|...|......:|   ||:.::..:                ...:|    ..|..::
  Rat   406 CVNFIESALPYVVGKMFVNVH---FQEDKKEMMEELIEGVRWAFIDMLEKENEW----MDAGTKR 463

  Fly   411 KELQVARIL---QNHAENYLNITELNENYEGLKLEKNSFYANLLILRRAQLRHSF---------V 463
            |..:.||.:   ..:.|..:|.|.:||:.:.:|..::.::.|:|..|:...:..|         .
  Rat   464 KAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFWLRKAVPKT 528

  Fly   464 SPYVDEEDVNQPAYFLRHFLHFVLLSLHRPTY-------------------HYYATHGLELWRES 509
            ..:.:...||.......:.:.|....|.:|.:                   |.: |||.:   .:
  Rat   529 EWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEF-THGFD---NN 589

  Fly   510 RLLLDTDGH---YTAMDCLER---------QSFQHYDAKLAPI----YRPLGSH-----EIAEIF 553
            ....|.:|:   :.::|..|:         ..:.:|..|.|.:    .|.||.:     .:.|.|
  Rat   590 GRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAF 654

  Fly   554 QFYRSFQYSLTDYHFWLQGERFAFAETFVLDYFGLNPHRVLFYAVAQQLCN--------RQTEIF 610
            :.||.          |:...|....|. :|.......:::.|.:.|...||        .|.:|.
  Rat   655 RAYRK----------WINDRRQGVEEP-LLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIG 708

  Fly   611 A-----AQLNRGYMNLPEFQEAFKCGAEKAMN 637
            |     .::|....|..|||:||.|.|...||
  Rat   709 AHSPPQFRVNGAISNFEEFQKAFNCPANSTMN 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	6/21 (29%)
		GluZincin	<579..642	CDD:301352	20/72 (28%)
Phex	NP_037136.2	M13	74..740	CDD:341056	131/742 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340894
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930