Protein Alignment Nepl9 and nep-8

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 133/646 - (20%)
• Similarity: 222/646 - (34%)
• Gaps: 234/646 - (36%)

  Fly    49 NLQQLVKIKND-------------------------SMDPCDDFYAHACGNFDQTKEENSDDFLP 88
            ||.:|:.|.||                         |:|||.||:.|:||.|.:.....|.....
 Worm    39 NLDELLSIGNDVDSKNLCDSPECITLSHELLNYQDPSVDPCVDFFQHSCGRFHEQSVSESRLQKK 103

  Fly    89 PYLYNKQDRMNFFTAEVGNFETIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLAR 153
            .::..||.|.  |..::.|..:....|:..::.:|...::.:       ..:::...|.|..:..
 Worm   104 KHILRKQIRE--FLHKIQNSTSKSENLMKLVFDKCEASKKTS-------NDNYKISRDAIHDVFN 159

  Fly   154 HKEVLSSWPFLKHQWERRR-------------------LYGQLNWIVLSAQLAAHGLPTL---LH 196
            ..:.:.:||.|...|:..:                   |: ||::.:|:........|||   :|
 Worm   160 DIKKIGAWPLLDKNWDGSKFDLNEMLSNLVKLGATNLGLF-QLDFRILTEGKFVRIAPTLGSIVH 223

  Fly   197 -------IYFALDTIYVSP-MEELPCP---------SIADFQSS--LSDVLEG-RHHQVSRIIS- 240
                   |...|:...|.| .||:...         .:|.:|||  ||..|.| |....|.:|:
 Worm   224 NSTMISMISEILEANGVQPDSEEISKEFEEYSSLQMKLAKYQSSGKLSISLPGVRSINFSSLITE 288

  Fly   241 --HEMRV-----LCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQYFAALNF--- 295
              |..||     ..|.:..|.||....::....:|         :.|:|.:.....|...|:
 Worm   289 MIHPSRVSKIFGKIRVVTSEHPLFFKSNETESLDT---------IIESTSNKTLANFLIFNYIQS 344

  Fly   296 SEERLVGARK----------FP-----------LD------VEKITQ-----AWEVLRHTETRIV 328
            |...:.|||:          ||           :|      |:|:|:     ..|:::.||
 Worm   345 SYNIMKGARRGNCEDDVRREFPRASLRVFMRNFVDKGNRDGVKKLTEELKKNTLEMIQDTE---- 405

  Fly   329 YNYV------MWQAREQLR----YPDCY----RVSEEFERLLHAEYWQWHVLRRHLSREVALASY 379
             |..      |.:..|.::    |||.:    .:.:|||                        ::
 Worm   406 -NLAPPVKESMLKKVEAIKVTIGYPDHFDPPGTLDKEFE------------------------NF 445

  Fly   380 QLHTTR-----FQKLRRSKLSRR-DWYGHLWPASVEKKELQVARILQNHAENYLNITELNENYEG 438
            .|.:|.     ||||.|.:..:: ::.....|.|..|:.|:|                 |.||
 Worm   446 DLDSTDSYYRIFQKLNRLRSEQQMEFIAGETPISPIKEVLKV-----------------NANY-- 491

  Fly   439 LKLEKNSFYANLLILRRAQLRHSFVSPYVDEE--DVNQPAYFLRHFLHFVLLSLHRPTYHYYATH 501
             |..||:.              :..:|::|:.  |:..|.|....|..|::.   ....|....:
 Worm   492 -KRSKNAL--------------TVFAPFLDDPFFDITYPDYVNLFFSGFLIA---HEIGHSVDAN 538

  Fly   502 GLELWRESRLLLDTDG----HYTAM----DCLERQSFQHYDAKLAPIY--RPLGSHEIAEI 552
            ||......:.:   ||    |.|..    .||..| :.:||   .|:|  :..|:|.|.||
 Worm   539 GLGYDENGKPM---DGIRLEHVTEYGKQGQCLVDQ-YDNYD---DPVYGKKMNGTHSINEI 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	126/608 (21%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	126/609 (21%)