Protein Alignment Nepl9 and nep-4

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_509156.2
• Gene: nep-4 / 183746
• WormBaseID: WBGene00016896
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 104/668 - (15%)
• Similarity: 188/668 - (28%)
• Gaps: 305/668 - (45%)

  Fly    42 FSHLYKSNLQQLVKIKNDSMDPCDDFYAHAC--GNFDQTKEENSDDFLPPYLYNKQDRMNFFTAE 104
            :.|.:......|.||.:...|||||||.|||  |:.        :|.:...:...:|.:|....:
 Worm    16 YEHPFDFIENALEKIVDWKSDPCDDFYRHACPVGSI--------EDIIKVSMQPLKDALNHSWKQ 72

  Fly   105 VGNFETIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLSSWPFLKHQWE 169
            .|                  :|.|..|:......||
 Worm    73 KG------------------QRNEGKVYNINFRRSH----------------------------- 90

  Fly   170 RRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALD---TIYVSPMEELPCPSIADFQSSLSDVLEGR 231
                            :..|....||.||:...   ..||:..:.:..|.....:::::|.:...
 Worm    91 ----------------ICCHFFCKLLFIYYDYQYRFINYVTFYDGMLQPLYYHVEANVTDGINEI 139

  Fly   232 HHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQYFAALNFS 296
            |..:.
 Worm   140 HQMME------------------------------------------------------------ 144

  Fly   297 EERLVGARKFPLDVEKITQAWEVLRHTETRIVYNYVMWQAREQLRYPDCYRVSEEFERLLHAEYW 361
                        |:.::...|  |..|.         |.....|        :||.:.:.:|
 Worm   145 ------------DMVELGNIW--LEKTP---------WVINNNL--------TEEMKNITNA--- 175

  Fly   362 QWHVLRRHLSREVALASYQLHTTRFQKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAENY 426
                    :...|:|..|    |.|                            :..:|.....::
 Worm   176 --------IKMPVSLTKY----TNF----------------------------IYNLLSPIETDF 200

  Fly   427 LNITELNENYEGLKLEKNS----FYANLLILRRAQLRHSFVSPYVDEEDVNQPAYFLRHFLHFVL 487
            ||..   ..:||  ::.|:    ||:..:.:|   .|.|:   ::|:...|........|
 Worm   201 LNCV---SEFEG--IQNNTLFCLFYSAKIFVR---TRGSY---FIDDNGYNAEGTIYFGF----- 249

  Fly   488 LSLHRPTYHYYATHGLELWRESRL------------------LLDTDG--HYT--AMDCLERQSF 530
                 |.| |:.|:|  .||.|:|                  .::.||  :::  |.||::.|..
 Worm   250 -----PNY-YHTTYG--NWRASKLGYTGTRVGHEIGHTFIEHSINPDGLPYFSKPAEDCVQNQYL 306

  Fly   531 ----QHYDAKLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQGERFAFAETFVL-------- 583
                ::|:               .|:.....:..|:..|....:.|.:.|:|   :|
 Worm   307 KTCNEYYE---------------GEVPDACNTSDYTFDDNGADVFGLQLAYA---ILERDLSDQL 353

  Fly   584 ----DYFGLNPHRVLFYAVAQQLCNRQTEIFAAQLNRGYMN--------LPEFQEAFKCGAEKAM 636
                |...:...::|||:.|.:.| |.::......:..:.|        :|.||:||.|.::..|
 Worm   354 REQADGLKITNEQLLFYSFAYRFC-RGSKSNTTDGSHSHHNVRINAVAQMPGFQQAFNCASDSRM 417

  Fly   637 --NPPSRCMINMCERPHT 652
              :...:|:|.....|.|
 Worm   418 MKSATKQCVIYGNNAPET 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	11/23 (48%)
		GluZincin	<579..642	CDD:301352	16/84 (19%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:387391	38/196 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900