Protein Alignment Nepl9 and nep-22

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 812
• Identity: 136/812 - (16%)
• Similarity: 237/812 - (29%)
• Gaps: 298/812 - (36%)

  Fly    46 YKSNLQQLVKIKNDSMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFT---AEVGN 107
            |......|:...:|::|||.||||..|..|.|    |:|       ..|..|....|   |:|..
 Worm    68 YTQAANYLLNGLDDTVDPCQDFYAFTCNKFLQ----NTD-------LQKLGRSRLGTYDQAQVDV 121

  Fly   108 FETIPGRL--ISQLYTECRKRE----------ERNVFTP--------TRLTSHWERMLDEIPFLA 152
            :..|...|  |....|...|.|          :.|:.:|        ..:||    :...:||..
 Worm   122 YSEIVAALSKIDVTSTTTSKTERITKAAFETCKNNLASPADKTAVVYAEITS----LFGGVPFFG 182

  Fly   153 RHKEVLSSWPFLKHQWERRRLYGQLNWIVLSAQLAAH-------GLPTLLHIYFALDTIYVSPME 210
            ...:....:..:..|.|::...|.|.:.:.|:....|       |.|.|   ..|.| .||.|.
 Worm   183 EPLKTNVDYWMVAGQIEQKHAVGTLTYTIASSDYKDHTKNALYTGPPGL---SLARD-FYVKPQ- 242

  Fly   211 ELPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQ 275
                 .||:....:|||.:                          |:.:.:...:.|.   |.:.
 Worm   243 -----YIAEVNQRVSDVND--------------------------LLTAFANAAKKNV---GADA 273

  Fly   276 LLLDENTMDYFQQYFAALNFSEERLVGARKF-----PLDVEKITQAWEVL--------------- 320
            ||.....:..|:...|..::.::.|   |.:     |.::...|.|:..:
 Worm   274 LLAAAQEVVNFEVQIAMASWPDDLL---RNYQQQYNPYNIASATTAYRAINWKSYLGQLFHGVAS 335

  Fly   321 --------------------------RHTETRIVYNYVMWQ------------------------ 335
                                      :.:.:.:|.||::.|
 Worm   336 DADQANYNIVVTEPSYFAWLNSVFDGKTSNSTVVANYMIAQLLADESDFINPATAKVSSDTNYIH 400

  Fly   336 ------------AREQLRYPDCYRVSEEFERLLHA--EYWQWHV-LRRHLSREVALASYQLHTTR 385
                        .:.:.|..|...:||....||.|  .|...:| ::....|....|..:..||.
 Worm   401 YALRNGRGIKKIGKREYRMADLDGISEGCMDLLTAYMPYGTGYVYVKSKSERNKVQADVKDQTTL 465

  Fly   386 FQKLRRSKLSRRDW-------------------YGHLWPASVEKKELQVARILQNHAENYLNITE 431
            .....:..:...:|                   :|  ||.:           :.....::..:..
 Worm   466 IINNFQGMIDSLNWMDTFSKNRAHNKSDSLVKNFG--WPEA-----------MFGDFNDFTTVDA 517

  Fly   432 LNENYEGL----KLEKNSFYANLLILRRAQLRHSFVSPYVDEED----------VN---QPAYFL 479
            .|::|..:    ..:||..|....:|::......|.....:..|          ||   ||.
 Worm   518 YNQDYASIIDLYTKDKNDIYGIFAVLKKGMEVREFFRIMGEPADRTNFLQSPAMVNAWYQPE--- 579

  Fly   480 RHFLHFVLLSLHRPTY----------------------HYYATHGLELWRESRLL---------L 513
            |:.:.|...:.:.|.|                      |.|...|::......|.         :
 Worm   580 RNSITFPYAAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEGVQFGFNGELTDCSWNKCGWM 644

  Fly   514 DTD---GHYTAMDCLERQ-SFQHYDAKLAPIY------------RPLGSHEIAEIFQFYRSFQYS 562
            ||:   |......|:..| |.|....|...|:            ..||..:.|     |||::..
 Worm   645 DTNSSSGFIDMAQCVVTQFSTQCCPEKTGNIHCANGATTQGENIADLGGQQAA-----YRSYRQY 704

  Fly   563 LTDYHFWLQGERFAFAETFVLDYFGLNPHRVLFYAVAQQLCNRQTEI-FAAQL------------ 614
            :......::.:|....|.:       .|:::.:.......|.:|::. ...||
 Worm   705 VATTRKGVEEDRLPGLENY-------TPNQIFWITYGYSWCMKQSDANLVHQLLTNPHSPAQCRT 762

  Fly   615 NRGYMNLPEFQEAFKC--GAEKAMNPPSRCMI 644
            |:...::|||.:.|.|  |:.....|..||.:
 Worm   763 NQVMQDIPEFGKDFGCVRGSPMYPEPSGRCKV 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	11/21 (52%)
		GluZincin	<579..642	CDD:301352	14/77 (18%)
nep-22	NP_509528.1	PepO	76..795	CDD:226118	134/804 (17%)
		M13	83..793	CDD:189000	132/794 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810