Protein Alignment Nepl9 and nep-26

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 779
• Identity: 161/779 - (20%)
• Similarity: 267/779 - (34%)
• Gaps: 273/779 - (35%)

  Fly    52 QLVKIKNDSMDPCDDFYAHACGNF-DQTKEENSDDFLPPYLYNKQ----DRMNFFTAEVGN---- 107
            :|:|..:.|::|||:||..|||.: :|:.....|.:  ..||..|    |::.....::.:
 Worm   115 RLLKRVDQSVEPCDNFYQFACGGWINQSVNLKYDSW--NTLYETQRTAHDQIVQAMHKINDGSYP 177

  Fly   108 FETIPG-RLISQLYTECRKREERNVFTPTRLTSH-WERMLDEIPFLARHKEVLSSW-PFLKH--- 166
            ..|..| |..:::|.:|.   :.:....|.|  | |||.:||          |..| |.||:
 Worm   178 LPTNAGERAAAKMYEQCM---DTDTLEQTGL--HLWERFVDE----------LGGWMPELKNGAL 227

  Fly   167 -----------QWERRRLYGQLNWIVLS-----------AQLAAHGLPTLLHIYFALDTIYVSPM 209
                       :.|::|...::..|:||           |.:..:.|.:..|    |.|||
 Worm   228 EQEESFEIELDEDEKKRRRFEIEDIILSAFNYSVFPLFWAGVEVNYLNSKEH----LITIY---- 284

  Fly   210 EELPCPSIADFQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEE 274
            |:||.            :|....:..::.::.||  :..:|.|. |:.|:|.|        .|||
 Worm   285 EQLPI------------LLAPEKYHYNKELTPEM--IYGKMEGP-PVTRALQQ--------VGEE 326

  Fly   275 QLLLDENTMDYFQQYFAALNF----SEERLVGARKFPLDVEKITQAWEVLRHTETRIVYNYVMWQ 335
                          ..|.|.|    .:.|::.|....|:.: ||.|.... :.|.:..|..||.:
 Worm   327 --------------LSAVLGFDSTDEKVRMMIANMIYLEYQ-ITMAGSTF-YKEKKERYTVVMLR 375

  Fly   336 AREQLRYPDC---YRVSEEF-ERLLHAE------YWQW--------HVLRRHLSREVALASYQLH 382
            ..:::. |..   |.:|... |.|.|:|      ..||        ..|::..|....|.:|...
 Worm   376 ELQEIA-PAINWHYFLSRLVGENLSHSEPIALKTGTQWIPILSAIVEKLKQSRSGVAVLKNYVKW 439

  Fly   383 TTRFQKLRRSKLSRRDWYGHLW-------PASVEKKELQVARI---------------------- 418
            .|....|..:....||  |.||       .|:.::||..|.|:
 Worm   440 KTIMFHLAYASPKCRD--GLLWMAVSLYSGAASQRKEFCVLRLSGIFPLSLPSILRKIDGIDHTE 502

  Fly   419 -----LQNHAE-------------NYLNITELNENY-------------------------EGLK 440
                 :||.|:             |..:..|..||.                         |.::
 Worm   503 KNVKAVQNIADRIQEKYEEMVRSSNLFSDRETRENVIDKVNNMTKFIGFPDAMRSDYEMEKEAVR 567

  Fly   441 LEKNSFYANLL--------ILRRAQLRHSFVSP--YVDEED-VNQPAY-FLRHFLHFVLLSLHRP 493
            |....|::.:|        .|:|.:|.   |.|  :||... ::.||: :.|:.:.....||..|
 Worm   568 LHDTLFWSMVLGSSSVYKERLQRLRLP---VDPRSWVDTRPAISVPAHNYERNLVQIPFDSLRLP 629

  Fly   494 TYHYYATHGLELWRESRLLLDTDGHYTAMDCLERQSFQH-YDAKLAPIYRPLGSHEIAEIFQFYR 557
               |...|.|:.           .:|..:..:......| :|.: ..::.|.|:..:.......|
 Worm   630 ---YADEHQLDF-----------ANYAGIGTIIGHELTHAFDGQ-GKLHGPTGNLGVWWSTDSIR 679

  Fly   558 SF---------QYS-LTDYHFWLQGERFAFAETFVLDYFGL------------------------ 588
            .|         ||: |.|.|.....:...:..  :.|..||
 Worm   680 EFKAREQCFVKQYAGLMDSHDMNAAKEGLYEN--IADQVGLKVAYEAWKSNGNQNSGRMPGLEKY 742

  Fly   589 NPHRVLFYAVAQQLCNRQTEIFAAQ--------LNRGYMNLPEFQEAFKCGAEKAMNPPSRCMI 644
            :..::.|.|..|..|..:::.:..|        :.....|.|||..|:||.:|..||||.:|.|
 Worm   743 SQDQLFFLAYTQGWCALRSKSYKLQPHMEERIRMLGSLQNSPEFASAWKCSSESFMNPPDKCSI 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	156/765 (20%)
nep-26	NP_001022540.1	M13	124..805	CDD:341056	156/767 (20%)