Protein Alignment Nepl9 and nep-5

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001364754.1
• Gene: nep-5 / 173933
• WormBaseID: WBGene00017393
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 123/696 - (17%)
• Similarity: 253/696 - (36%)
• Gaps: 225/696 - (32%)

  Fly    52 QLVKIKNDSMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIPG--- 113
            :|:::.:.|::||::|:.|.|..|:..|:    ||         :|:    .::.|.:..|.
 Worm   119 ELLELMDSSVNPCENFHHHVCNGFNPRKK----DF---------ERL----MKLINIQEKPDHRK 166

  Fly   114 --RLISQLYTECRKREERNVFTPTRLTS-------------HWERMLDEIPFLARHKEVLSSWPF 163
              .::.::.::|...:...:....||:|             .|.:..|  |....:.....|:||
 Worm   167 AVNVVRRMLSKCAMGKTEEIHQVGRLSSIILPGLPFPLLNNSWTKPSD--PISTSNSSTTYSYPF 229

  Fly   164 LKHQWERRRLYGQLNWIVLSAQLAAH--------GLPTLLHIYFALDTIYVSPMEELPCPSIADF 220
            |..               :.|.:..|        |:.......|:|  ..|.|..    |.:.:|
 Worm   230 LTK---------------ILAHIILHNPDDAGFVGIKPSSDSEFSL--FVVKPFS----PVLTNF 273

  Fly   221 Q-SSLSDVLE----------------GRHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNT 268
            : .::.|:|:                .|..|::.:|..:.::...|.:.: |.|.:|::..|
 Worm   274 KFRNMYDILKRNAPESSTNGMIDLEFDRQRQLNDVIKLQTKLEKIEFKAD-PEVVNLTEIQR--- 334

  Fly   269 SRPGEEQLLLDENTM--DYFQQYFAALNFSEERLVGARKFPLDVEKITQAWE----VLRHTETRI 327
                 :..::|...:  .:....:|.|   :|::.|..         |..:|    ::..|.:..
 Worm   335 -----QMPIIDWKRLIDSWIPNGYAHL---KEKVYGFN---------TSYYEEINAIISSTPSET 382

  Fly   328 VYNYVMWQAREQLRYPDCYRVSEEFERLLHA---EYWQWHVLRRHLSREVALASYQ--------- 380
            :||::.            .|.|.:|.|...|   |....|.|...:..::.|...:
 Worm   383 IYNFLF------------LRFSFKFLRTEVASDLEDTCLHQLSTTIPGKIVLYGSEEPEALNLLN 435

  Fly   381 --LHTTRFQKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAENYLNIT--ELNENYEGLKL 441
              |||.:.| |:|| |:...|        ::.:.::.|:...|..:.....|  :|.:...|...
 Worm   436 GMLHTIKDQ-LKRS-LATLKW--------MDSRGIEEAQKKFNKTKTVFGFTGEDLIDELVGKIT 490

  Fly   442 EKNSFYANLLILRRAQLRHSFVSPYVDEEDV----NQPAYF---------LRHFLHFVLLSLHRP 493
            .::::.:.|..:...|.|:.|.|  |.|.:|    |...::         .|..||:..:|.:.|
 Worm   491 PESNYISTLQNVLLWQTRNMFKS--VAENNVTVFLNSEVFYSVEKNEITISRALLHYPFMSANLP 553

  Fly   494 TYHYYATHGLELWRESRLLLDTDGHYTAMDCLERQSFQHYDAKLAPIYRPLGSHEIAEIFQFYRS 558
            .|..:||...::..:...:.|..|.:             ||:.        |:|         |:
 Worm   554 NYTNFATIASKILPQMIHIFDERGRF-------------YDSD--------GNH---------RN 588

  Fly   559 FQYSLTDYHFWLQGERFAFAETFVLDYFGLN-------------PHRVL------------FYAV 598
            :..:.|:.:|.:..:.|   :..:.:.||::             |:..|            ||::
 Worm   589 WWNTETERYFQIIVQCF---DGMMQNVFGVSVSIGWNAYDSTKEPYATLPGIQQSSDEALFFYSM 650

  Fly   599 AQQLCNRQTEIFAAQLNRGYMNLPEFQEAFKCGAEKAMNPPSRCMI 644
            .:.:|....:    .:|....::|:|..||||.....||||::|.:
 Worm   651 VKTMCTSDPD----NVNEALASVPQFNSAFKCNNGTKMNPPTKCKL 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	7/21 (33%)
		GluZincin	<579..642	CDD:301352	18/87 (21%)
nep-5	NP_001364754.1	GluZincin	128..691	CDD:417498	120/684 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900