Protein Alignment Nepl9 and nep-3

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 670
• Identity: 130/670 - (19%)
• Similarity: 258/670 - (38%)
• Gaps: 186/670 - (27%)

  Fly    50 LQQLVKIKNDSMDPCDDFYAHACGNFDQ----------TKEENSDDFLPPYLYNKQDRMNFFTAE 104
            :.||:..::.|:|||::||..|||.:::          .|::.....:..:|:..|..    |::
 Worm    71 VHQLLNFQDPSVDPCENFYQAACGKYNEHNVIDGSRTAQKQQIVKRLIRDFLHKNQSS----TSK 131

  Fly   105 VGNFETIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLSSWPFLKHQWE 169
            ..|       .:..||.:|::.:...|...       :.:|.|| |:...|  :.|||.|...|:
 Worm   132 SEN-------SMKLLYEKCKEAKTIKVLGN-------QNLLQEI-FMNIQK--IGSWPVLDENWD 179

  Fly   170 RRRLYGQLNWIVLSAQLAAHGLPT--LLHIYFALDT-IYVSPMEELPCPSIADFQSSLSDVLE-- 229
            .::.  .||.::||  |...|:..  ...|..:.|. :.:.|....|.      :.:|||::.
 Worm   180 GKKF--NLNEMLLS--LIRLGVSNFGFFEIIISSDAFVEIKPARNFPT------RENLSDIISKV 234

  Fly   230 --GRHHQVS-RIISHEMRV---LCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQ 288
              |...|.: ..|.:::|.   |.||::....|:::....:..|
 Worm   235 FLGNGFQPNITAIENDLREYENLQRELKSLERLIQTTPNRSLVN--------------------- 278

  Fly   289 YFAALNFSEERLVGARKFPLD-VEKITQAWEVLRHTETRI-VYNYVMWQAREQLRY-----PDCY 346
             :...|:.:..::..::.|.: .|.:  ..:.|....||: |.|::   .:|..:|     .|
 Worm   279 -YLIFNYLKSVMLEYKRLPEEQCEGV--VIDFLPRASTRVFVQNFL---DKENRKYVAGMIED-- 335

  Fly   347 RVSEEFERLLHAEYWQWHVLRRHLSREVALASYQLHTTRFQKLR--RSKLSRRDWYGHLWPASVE 409
             |...|..::....|     ....|::||:          ||::  :|.:...|::..  |.:::
 Worm   336 -VKMGFIDMIQESTW-----LNEESKKVAV----------QKVKNIKSMIGYPDFFEP--PGTLD 382

  Fly   410 K--KELQVARILQNHA-----ENYLN-------ITELNENYEGLKLEKNSFYANLLILRRAQLRH 460
            :  |:|.:.:....|.     :.:.|       .:|:..:.....|..|:||.|...|
 Worm   383 RSFKDLNIEQTDSYHTIVRKIQKFTNEQCMEFVASEIPLDPRQPILHANAFYQNTNFL------- 440

  Fly   461 SFVSPYVDEE--DVNQPAYFLRHFLHFVLLS--LHRPTYHYYATHGL--------ELWRESRLLL 513
            :.::|.:|:.  |...|.|     ::..::.  |.....|.:...|:        .:|....
 Worm   441 AILAPVLDDPIFDTTFPRY-----VNLAVIGNVLAHEIGHAFDHTGINYDDAGQQRIWLTPE--- 497

  Fly   514 DTDGHYTAMDCLERQSFQHYDAKLAPIYRPL-GS---HEIAE----IFQFYRSF-QYSLTDYHFW 569
            |::.:...:.||.||..::.|....   |.| ||   |||:.    :...:|:| :..|::
 Worm   498 DSEEYGKRLRCLLRQHDEYDDPDFG---RNLNGSKTLHEISADRFGVEAAWRTFKKLDLSN---- 555

  Fly   570 LQGERFAFAETFVLDYFGLNPHRVLFYAVAQQLCNRQ--TEI-FAAQ---------LNRGYMNLP 622
                     |:.::.:...|..::.|...|...|.::  |:: :|.|         :|..|.|:|
 Worm   556 ---------ESEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQREHPTNNFRVNGIYANMP 611

  Fly   623 EFQEAFKCGAEKAMNPPSRC 642
            :|.|.|.|.....|||..:|
 Worm   612 QFAETFNCPLGSPMNPKKKC 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	126/656 (19%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	126/657 (19%)