Protein Alignment Nepl9 and nep-9

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 140/719 - (19%)
• Similarity: 246/719 - (34%)
• Gaps: 222/719 - (30%)

  Fly    51 QQLVKIKNDSMDPCDDFYAHACGNF-DQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIPGR 114
            |:|....:.:...|:|||...|.|: |....:...|.......||..| .|...:...|.:....
 Worm    74 QELKAYSDTATKSCEDFYKATCENYKDHQALDRHRDCKKRKAVNKLVR-GFLQRDESTFTSESES 137

  Fly   115 LISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLSSWPFLKHQWERRRLYGQLNW 179
            .|..::.:|.:.        :|.||:    ||    :.:..:.:.|||.|:|.|:.    ...|.
 Worm   138 AIKLIFGKCDEL--------SRNTSY----LD----IFKDIKKIGSWPVLEHNWKD----SMFNL 182

  Fly   180 IVLSAQLAAHG----------LPTLLHIYFALDTIYVSPMEE-------------LPCPSIADFQ 221
            ..:.|:|...|          |..|...:||   ::||..:|             |....|...:
 Worm   183 DDVIAKLVKLGSTDFGLFKLELRKLAFGHFA---VFVSSKQEQNIHQLEKTILGILKANGIQQDR 244

  Fly   222 SSLSDVLEG----RHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENT 282
            ..|||.|:.    ::| :......|..:..|...|.  :|.:|..::.|.       |:.|....
 Worm   245 KELSDDLKDYSDFKNH-LKEFYQEETYIEYRLYAGS--IVENLGISSLTT-------QMALKSTG 299

  Fly   283 MDYFQQY-------FAALNFSEERLVGARKFPLDVEKITQAWEVLRHTETRIVYNYVMWQAREQL 340
            :|.|...       .::|.|.||..:|.               :::.|..|.:.|::::...:.:
 Worm   300 LDVFNHVNQRTLITNSSLFFGEENNLGM---------------IIQKTPKRTLANFLIFHFIDVM 349

  Fly   341 R--YPDCYRVSEE--FERLLHAEYWQWHVLRRHLSRE------VALASYQLHTTRFQKLRRSKLS 395
            .  ..:..:..:|  .:.|..|..   .||.|:...|      |.:|. .|.|...:.:..|...
 Worm   350 TTDLANATKACKETLIDLLPRASI---QVLSRNFVNEDAQDDMVKMAQ-DLKTKITEMIDNSPFF 410

  Fly   396 RRDWYGHLWPASVEKKELQVARILQNHAENYLNITE-----LNENYEGLKL-EKNSFYANLLILR 454
            .:  :..::.|..:||.:|..:.:.       .:||     |:.::|.|.| ..:|.|..:..||
 Worm   411 TK--FHLVFDAEEQKKLIQKVKAIG-------IVTEYPQEVLDRDFERLNLTPSDSIYRTIQKLR 466

  Fly   455 RAQ----LRH-------------------------SFVSPYVDEE--DVNQPAYFLRHFLHFVLL 488
            |.:    :.|                         :..:|.:|..  |.:.|.|..:..:.|:|
 Worm   467 RLRSEQLIEHLGGDLDPTDTRVWGSAHYDQTTNNLTIFAPIIDGPYFDTSYPNYVNQFLMGFIL- 530

  Fly   489 SLHRPTYHYYATHGLELWR---ESRLLLDTDGHYTAMDCLERQSFQHYDAKL---APIY----RP 543
                         |.||.|   ..|:..|..|.  ..:.|:.:|.:.:|..|   |..|    .|
 Worm   531 -------------GRELGRSLDSVRIRKDEKGQ--TENWLKPESLKRFDEHLKCWAEKYDKSADP 580

  Fly   544 LGSHE--IAEIFQFYRSFQYSLTDYHFWLQGERFA---------------------FAETFVLDY 585
            |.|..  |.:|...|             :|.|.||                     ..|||.:
 Worm   581 LKSESKGIRQIEGRY-------------IQNEMFADFIGHEASWRAFMKLDVKNEEVLETFKV-- 630

  Fly   586 FGLNPHRVLFYAVAQQLC------------NRQTEIFAAQLNRGYMNLPEFQEAFKCGAEKAMNP 638
              :...|:.|...|...|            ....:.::.::|..:.|:|:|..||:|.::..|||
 Worm   631 --IKLRRMFFNVQALYFCRPPSGSTDWLSYQEHHQHYSFRVNGAFKNMPQFALAFECASDDDMNP 693

  Fly   639 PSRC 642
            .::|
 Worm   694 QNKC 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	137/706 (19%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	138/706 (20%)