Protein Alignment Nepl9 and nep-13

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 721
• Identity: 142/721 - (19%)
• Similarity: 251/721 - (34%)
• Gaps: 218/721 - (30%)

  Fly    53 LVKIKNDSMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIPGRLIS 117
            |:..:|.::|||:|||.::||.:   :|...:|.:..   |::|             ||..:||.
 Worm    96 LLNWQNTNIDPCEDFYEYSCGRY---QEHTLNDGIRA---NEKD-------------TIVMKLIR 141

  Fly   118 Q------------------LYTEC--RKREERNVFTPTRLTSHWERMLDEIPFLARHKEV----- 157
            |                  ||.:|  |.|.|.                       ||:|.
 Worm   142 QFVLKNQSTTSNSENALMLLYEKCSLRYRMEN-----------------------RHQETEVIQR 183

  Fly   158 --------LSSWPFLKHQWERRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPC 214
                    :.|||.....|.....  .|| .:||...:.|.||..|   |....|.:.||
 Worm   184 EVFENIRKIGSWPIADKNWNSSHF--NLN-NMLSNMASIHMLPFGL---FETRVIELYPM----- 237

  Fly   215 PSIADFQSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPL--VRSLSQNTRTNTSRPGEEQLL 277
                   ::.:..|..|..::...|..|  .|.|.:|..|.:  :.|:.:..:.:.:    |...
 Worm   238 -------NTTAKQLVIRPTKLKFSIPQE--ELVRAIRDLLSVNGITSIMKKVKEDVA----ESFA 289

  Fly   278 LDEN-------------TMDYFQQYFAALNFSEERLVG------------------ARKFPLDVE 311
            ||:.             |:...|:....::|  ||::.                  :.:|.|...
 Worm   290 LDKEIGNIHIDPQPKPATLSELQKAVPDIDF--ERIIKSYLNPKTGNWSSLRTKIFSARFELFFG 352

  Fly   312 KITQAWEVLRHTETRIVYNYVMWQAREQLRYPD-CYRVSEEFERLLHAEYWQWHV---------- 365
            |......::..|:.||:.||:.      |:|.: .|....:..::...:.:...|
 Worm   353 KNNNLSSIIARTKPRILANYLF------LKYIEYAYFFFFDNTKVFSDDDFCTEVVTTSLPRASL 411

  Fly   366 ---LRRHLSRE-VALAS--YQLHTTRFQKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAE 424
               :|.|..:| :|:||  .::..|.:.::    ::...|..:....|..:|.:::.::: .:.|
 Worm   412 RVFVRNHFKKENMAVASEIVEVVKTAYVEI----INNSTWLHNSTRESAIEKVVKMKKVI-GYTE 471

  Fly   425 NYLNITELNENYEGLKLEK-NSFYANLLILRRAQLRHSFVSPYVDEEDVNQPA---------YF- 478
            .|.....|:|.:|.|:|.: :||:..:..:.|.::..  :..:|..:.:..|.         ||
 Worm   472 EYERTGALDEMFETLQLSRSDSFFVLMTKVNRFKIEQ--LMDFVSSDSLLNPIEPLVMANAFYFP 534

  Fly   479 -------LRHFLHFVLLSLHRPTYHYYATHGLELWRESRLLLDTDGHYT-----AMDCLERQSFQ 531
                   |..||...|.....|.|...|..|..|..|.....|.:|..|     ..|...|:..:
 Worm   535 TKNLLNVLVPFLDKPLFDFKYPRYVAMAGVGRVLAHEIGHAFDINGRQTDEIGRTRDWWTREDTE 599

  Fly   532 HYDAKLA-----------PIY--RPLGSHEIAEIFQFYRSFQYSLTDYHFWLQGERFAFAETFVL 583
            .||.:..           |.:  :..|:..:|||.......:.|      |:..::....|...|
 Worm   600 EYDRRSECFAEQFTNFKDPSFKGKQNGTEVLAEIIADALGMEAS------WIAFKKINLTEEQGL 658

  Fly   584 DYFGLNPHRVLFYAVAQ-QLC--NRQTEIFAAQL---------NRGYMNLPEFQEAFKCGAEKAM 636
            ..|..:....|::.||. ..|  :|..|.::.||         |..:.|...|.:.:||.....|
 Worm   659 IQFEDHDFGKLYFQVAALDFCAPSRIEERYSDQLSHPTNKFRINGAFSNSRAFADTYKCPVGSKM 723

  Fly   637 NPPSRC 642
            ||..||
 Worm   724 NPVQRC 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	9/21 (43%)
		GluZincin	<579..642	CDD:301352	19/74 (26%)
nep-13	NP_001342017.1	M13	104..729	CDD:189000	138/711 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900