Protein Alignment Nepl9 and Ecel1

DIOPT Version :10

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_067281.2
• Gene: Ecel1 / 13599
• MGIID: 1343461
• Length: 775
• Species: Mus musculus
• Alignment Length: 748
• Identity: 146/748 - (19%)
• Similarity: 259/748 - (34%)
• Gaps: 256/748 - (34%)

  Fly    60 SMDPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFT-AEVG--NFETI---------- 111
            |:|||.|||:.|||.:.:...      :|      .|::.:.| |.:|  |.|.:
Mouse   120 SIDPCQDFYSFACGGWLRRHA------IP------DDKLTYGTIAAIGEQNEERLRRLLARPTGG 172

  Fly   112 PG----RLISQLYTECRKREE------------------------------------------RN 130
            ||    |.:...:..|....|                                          :.
Mouse   173 PGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLYKAQG 237

  Fly   131 VFTPTRL-----------TSHWERMLDE----IP----FLARHKE---VLSSWPFLKHQWERRRL 173
            |::...|           :|.:...:|:    :|    :||:.:|   :|:::          |:
Mouse   238 VYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEESEKILAAY----------RV 292

  Fly   174 YGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPCPSIADFQSSLSDVLEGRHHQVSRI 238
            :.|....:|.|.........:|.:...|..|.||..::|.    .|..|:.:.|..|   |:.:|
Mouse   293 FMQRLLRLLGADAVEQKAQEILQLEQRLANISVSEYDDLR----RDVSSAYNKVTLG---QLQKI 350

  Fly   239 ISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDYFQQYFAALNFSEERLVGA 303
            |.|.                              :.:.|||:    .||:     :||||..|
Mouse   351 IPHL------------------------------QWKWLLDQ----IFQE-----DFSEEEEV-- 374

  Fly   304 RKFPLDVEKITQAWEVLRHTETRIVYNYVMWQA----REQLRYPDCYRVSEEFERLLH--AEYWQ 362
              ..|..:.:.|..:::|.|..||::||::|:.    .|.|..|        |...||  |:..:
Mouse   375 --VLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSSP--------FREALHELAKEME 429

  Fly   363 WHVLRRHLSR----------EVALASYQLH-------TTRFQKLRR-------SKLSRRDWYGHL 403
            .:...:.|:|          .:||.:..:|       ..:.|:|..       .:|...||....
Mouse   430 GNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAQ 494

  Fly   404 WPASVEKKELQVARILQNHAENYLNITELNENYEGLKLEKNSFYANLL--ILRRAQLRHSFVSPY 466
            ..|:...| ||...::..:.:..|....:::.|| .::.:.:::.|:|  |....||....:...
Mouse   495 TKAAARAK-LQYMMVMVGYPDFLLKPEAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQE 557

  Fly   467 VDEEDVNQP-----AYFLRHFLHFVL-LSLHRPTYH------------------YYATHGLELW- 506
            ||:.....|     ||:|.:....|. ..:.:||.:                  :..|||.:.|
Mouse   558 VDKSSWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWG 622

  Fly   507 ----RESRLL---LDTD-GHY-TAMDCLER--QSFQHYDAKLAPIYRPLGSHEIAEIFQFYRSFQ 560
                |...||   .:|. .|: ...:|:.|  .:|..|:.::.      |.|.:.|........:
Mouse   623 GQYDRSGNLLHWWTETSYSHFLRKAECIVRLYDNFTVYNQRVN------GKHTLGENIADMGGLK 681

  Fly   561 YSLTDYHFWLQGERFAFAETFVLDYFGLNPHRVLFY-AVAQQLCNRQ----------TEIFAAQL 614
            .:...|..|:: |.........|.|    .|..||: |.||..|.::          |:..|.:.
Mouse   682 LAYYAYQKWVR-EHGPEHPLHRLKY----THNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEH 741

  Fly   615 NRGYMNLPEFQE---AFKCGAEKAMNPPSRCMI 644
            .|...::.:|:|   ||.|..:..|||..:|.:
Mouse   742 YRVLGSVSQFEEFGRAFHCPKDSPMNPVHKCSV 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	144/742 (19%)
Ecel1	NP_067281.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..52
		M13	121..773	CDD:341056	144/744 (19%)