Protein Alignment Nepl9 and ece2

DIOPT Version :9

• Sequence 1: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 732
• Identity: 132/732 - (18%)
• Similarity: 248/732 - (33%)
• Gaps: 233/732 - (31%)

  Fly    61 MDPCDDFYAHACG----------------NFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFE 109
            :|||.|||.::||                .|:...::|.     ..|.:..:...|.::.....:
 Frog   115 IDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQ-----AILKHILENATFNSSSEAEMK 174

  Fly   110 TIPGRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHK------EVLSSWPFLKHQW 168
            |      .:.|..|.|                |:.::|:    |.|      |.:..|. :...|
 Frog   175 T------QRFYLSCLK----------------EQRIEEL----RQKPLTDLIEKIGGWN-ISGNW 212

  Fly   169 ERRRLYGQLNWIVLSAQLAAHGLPTLLHIYFALD--TIYVSPMEELPCPSIADFQSSLSDVLE-- 229
            .     |: |::.:        |.|:...|.|..  :::||          ||.:||.|::::
 Frog   213 R-----GE-NFMSV--------LKTVSGTYRATPFFSVFVS----------ADSKSSNSNIIQVD 253

  Fly   230 -------GRHHQVSRIISHEM-------RVLCREMRGELP-----------LVRSLSQNTRTNTS 269
                   .|.:.:::..:.::       .|...|:.|..|           ...:|..|......
 Frog   254 QSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQD 318

  Fly   270 RPGEEQLLLDENTMDYFQQYFAALNFSEERLVGARKFPLDV-----------EKITQAWEVLRHT 323
            ...:|:.:.:..|:...|....|.::.:.......  |||:           |.:.|..|::.:|
 Frog   319 ERRDEEKIYNRMTISELQSLAPAFDWMDYLTFALS--PLDLNDTEPVVVYGKEYLQQVSELVNNT 381

  Fly   324 ETRIVYNYVMWQAREQLRYPDCYRVSEEFERLLHAEY---------WQWHVLRRHLSREVALASY 379
            :..::.||::|...:::......|..:..::||.:.|         ||..:.....:...||.|.
 Frog   382 DPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSL 446

  Fly   380 QLHTTRFQK----LRRSKLSR-RDWY-----GHLWPASVEKKELQVAR-------ILQNHAENYL 427
            .:.:| |.|    :....:|. ||.:     |..|   :::|..:.|:       .:....:..|
 Frog   447 FVKST-FDKNSKNIAEQMISEIRDAFELTLGGLTW---MDEKTRRAAKEKADAIYDMIGFPDFIL 507

  Fly   428 NITELNENYEGLKLEKNSFYANLL------------ILRRAQLRHSF-VSPYVDEEDVNQPAYFL 479
            :..||:|.|:|.::.:::|:.|:|            .||:...|..: ::|    :.||  ||:|
 Frog   508 DTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTP----QTVN--AYYL 566

  Fly   480 --RHFLHFVLLSLHRPTY----------------------HYYATHGLEL---------WRESRL 511
              ::.:.|....|..|.|                      |.:...|.|.         |:.|.|
 Frog   567 PNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSL 631

  Fly   512 LLDTDGHYTAMDCLERQSFQHYDAKLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQGERFA 576
                :......:|:..|    |::......|..|...:.|........:.:...|..||    ..
 Frog   632 ----EAFKNRTECMVNQ----YNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWL----VK 684

  Fly   577 FAETFVLDYFGLNPHRVLFYAVAQQLCNRQTEIFAAQLNRGYM----------------NLPEFQ 625
            ..|...|...||..:::.|...||..|:.:|   ....:.|.:                |..:|.
 Frog   685 HGEEKQLPGVGLTNNQLFFVGFAQVWCSVRT---PESSHEGLVTDPHSPAKFRVIGTLSNSKDFA 746

  Fly   626 EAFKCGAEKAMNPPSRC 642
            |.|.|.....|||...|
 Frog   747 EHFNCPKGTPMNPGKHC 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	10/37 (27%)
		GluZincin	<579..642	CDD:301352	18/78 (23%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	131/730 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010