DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13282 and lpl

DIOPT Version :9

Sequence 1:	NP_001260521.1	Gene:	CG13282 / 35019	FlyBaseID:	FBgn0032612	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	376	Identity:	107/376 - (28%)
Similarity:	156/376 - (41%)	Gaps:	72/376 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SSTEGSTNPTPTSTTTPSNRDITIGPCKWAIGRSCPDPDVKYYIYTRHNPMDRQCLHIDESLEKS 102
            |..|.:.:||..|.|.   .||.....:|.:  ...|.:.|:...|...|.|..|..:..  :..
Zfish    24 SGLETTIDPTAESITL---SDIIGNATEWMM--DFTDIESKFSFRTLEEPEDDLCYIVPG--QPQ 81

  Fly   103 NLTDSYFNPRYPTKIIIHGYN-SDMFLHPLQQMREEYLAK---ADY------NIIYVDWSILSPG 157
            ::.|..||....|.|:|||:. :.||        |.::.|   |.|      |:|.||| :....
Zfish    82 SIKDCNFNTETKTFIVIHGWTVTGMF--------ESWVPKLVTALYEREPSANVIVVDW-LSRAQ 137

  Fly   158 PCYISAVHNTKHAGTCTAQLVERL---VETGNTDIHVIGFSLGAQVPNYIARNLSSFMLPRITGL 219
            ..|.::...||..|...|:.|..|   ::.....:|::|:||||.|.. ||..|:...:.||||:
Zfish   138 QHYPTSASYTKLVGKDVAKFVNWLQAEIDYPWEKLHLLGYSLGAHVAG-IAGLLTKHKVNRITGM 201

  Fly   220 DPAMPLFITSGKADKLDPSDASYVDVIHTNALVQGKMER-------CGHADFYMNGGIMQPGCNG 277
            |||.|.|..:.....|.|.||::|||:|||  .:|..:|       .||.|.|.|||..||||:.
Zfish   202 DPAGPTFEYADSLSTLSPDDANFVDVLHTN--TRGSPDRSIGIQRPVGHIDIYPNGGTFQPGCDL 264

  Fly   278 QKI-------------NSFACSHQRAPAYFLES-IRSPKGFWGWACSGYISYLLGMC-----PPT 323
            |..             ....|||:|:...|::| :........:.||...|:..|||     ...
Zfish   265 QNTMLMVATTGLRNMDQIVKCSHERSIHLFIDSLVNQDHESMAFRCSSRDSFNKGMCLSCRKNRC 329

  Fly   324 NFLLEAGENIRPTTRGMFMIDTNDSSPFAL----------GK----WTDLP 360
            |.:..|...||........:.|.:..|:.:          ||    :||.|
Zfish   330 NKVGYAVNKIRTRRSSKMYMKTREMMPYKVFHYQVKVHFFGKTQLSYTDQP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13282	NP_001260521.1	Lipase	67..351	CDD:278576	92/322 (29%)
CG13282	NP_001260521.1	Pancreat_lipase_like	75..347	CDD:238363	91/310 (29%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	98/343 (29%)
		Pancreat_lipase_like	56..353	CDD:238363	91/310 (29%)
		PLAT	360..484	CDD:294016	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010