DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13282 and Lipc

DIOPT Version :9

Sequence 1:	NP_001260521.1	Gene:	CG13282 / 35019	FlyBaseID:	FBgn0032612	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	XP_006243421.1	Gene:	Lipc / 24538	RGDID:	3009	Length:	510	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	118/486 - (24%)
Similarity:	191/486 - (39%)	Gaps:	136/486 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 PDVKYYIYTRHNPMDRQCLHIDES---------LEKSNLTDSYFNPRYPTKIIIHGYNSDMFL-- 128
            |::::.::.            |||         .....|.:..||..:|..:||||::.....
  Rat    47 PEIRFLLFK------------DESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSGSESATV 99

  Fly   129 -------HPLQQMREEYLAK----------ADYNIIYVDWSILSPGPCYISAVHNTKHAGTCTAQ 176
                   ..:..:.|.::.|          ...|:..|||..|: ...|..||.||:..|...|.
  Rat   100 GKDSDNDSQVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLA-YQHYAIAVRNTRVVGQEVAA 163

  Fly   177 L---VERLVETGNTDIHVIGFSLGAQVPNYIARNL-SSFMLPRITGLDPAMPLFITSGKADKLDP 237
            |   :|..::...:.:|:||:||||.|..:...:: ....:.||||||||.|:|..:...::|.|
  Rat   164 LLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSP 228

  Fly   238 SDASYVDVIHT-----NALVQGKMERCGHADFYMNGGIMQPGCNGQKI-------------NSFA 284
            .||::||.|||     ..|..|..:...|.|||.|||..||||:..::             .:..
  Rat   229 DDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIK 293

  Fly   285 CSHQRAPAYFLESIR-SPKGFWGWACSGYISYLLGMC-----PPTNFLLEAGENIR----PTTRG 339
            |:|:|:...|::|:: |.....|:.||...|:..|:|     ...|.|   |.:||    ..::.
  Rat   294 CAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSL---GYDIRRDRPRKSKT 355

  Fly   340 MFMIDTNDSSPFALGKWT-----------------DLPTLGAKQPQWRVPTQKLKAPPNQGVDPL 387
            :|:| |...|||.:..:.                 .:..||.|:...::|....:...:.....|
  Rat   356 LFLI-TRAQSPFKVYHYQFKIQFINQMEKPIEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSL 419

  Fly   388 LHHIDQ-FGKLA------------AN-FNNLQ---MWPTEQDPY-------EHWTSFSPEQKEND 428
            |..:|: .|:|.            || :|.:|   :|.||  |:       ..|......|:...
  Rat   420 LITLDKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTE--PHYAGLILKTIWVKAGETQQRMT 482

  Fly   429 SDGDSVEEQDPVEFIEPDDRQMISTEARPTQ 459
            ...|:|           ||.|:     .|||
  Rat   483 FCPDNV-----------DDLQL-----HPTQ 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13282	NP_001260521.1	Lipase	67..351	CDD:278576	89/335 (27%)
CG13282	NP_001260521.1	Pancreat_lipase_like	75..347	CDD:238363	88/331 (27%)
Lipc	XP_006243421.1	Lipase	18..366	CDD:278576	89/335 (27%)
		Pancreat_lipase_like	47..362	CDD:238363	88/331 (27%)
		PLAT_LPL	369..504	CDD:238856	27/147 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010