Protein Alignment Cse1 and KAP120

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_015200.1
• Gene: KAP120 / 855978
• SGDID: S000006046
• Length: 1032
• Species: Saccharomyces cerevisiae
• Alignment Length: 1090
• Identity: 203/1090 - (18%)
• Similarity: 395/1090 - (36%)
• Gaps: 240/1090 - (22%)

  Fly    24 NVRRPAEKLLESTELQQNYPILL----LNLIDKAQMDMTTRVAGAIAFKNYIKRNWAAHLDSDGP 84
            :|::.||:.|...|.|..:..||    |||.:..|:    |....|.|||.:.:.|.    |...
Yeast    26 DVQKLAEQQLRQWETQAGFHYLLQSIYLNLSNSLQI----RWLAVIQFKNGVDKYWR----STRI 82

  Fly    85 DRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQLI--------DEMVERF 141
            :.|.:.::.:|:..:..::......|..|.:.|.:.|.:.|||.:||.|.        ||::.:.
Yeast    83 NAIPKDEKASIRGRLFEMIDEQNNQLCIQNAQASARIARLDFPVEWPTLFEDLENLLNDEIIRKD 147

  Fly   142 ASGDFNVINGVLQTAHSL----FKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLTKVHE 202
            :...:|::..:.|....|    ..|.|     .|:..::..:|..:.:......:.....:.::.
Yeast   148 SVKIYNILMHINQIVKVLGTARIGRCR-----PAMQSKVPLILPLIVRIYLQSFEEWTTSSNLNY 207

  Fly   203 NNAGALKVIYGSLVLVNKV----------------FFSL----------NSQDLPEF--FEDNIN 239
            .:..:|:|.|.:|.::.::                |..|          |.::..:|  :|..|.
Yeast   208 EDLSSLQVSYLALKVLRRIICEGYDRPQTDQSVCDFIKLSVSHFEMLISNHENFKKFDIYEKFIK 272

  Fly   240 TWMGAFIQQLAADVPSLRTADDEDAGVLEHLRAQVCENICLYAKK-YDEEFKPFMEQF-VTA-VW 301
            . :|.....|....|:        ..:|.....|:   :..|.:. :|:..|.:.|.. ||. .|
Yeast   273 C-LGKLYFNLVTGSPA--------NFILLPCSTQI---LITYTRLIFDKAPKVYRENSDVTGDFW 325

  Fly   302 E-------LLVK---TSLHTKYDSLVSHALQFLSVVADRQHYQSIFENPEILAQICDKVVIPNLD 356
            |       |::|   ..:|.|....:......|::.|......:.|.|..::.::.|.::...|.
Yeast   326 EQTAIRGLLILKRVINFIHKKGAITLKARSDKLTIDASINKINTEFLNENLITRLVDTLMEWYLR 390

  Fly   357 IRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIFGQYLERLLTKYKE 421
            :||::.|.:...|||:|...: .:..:.:.|...:       |..|.:...|.:.|...|.|..|
Yeast   391 LRPTELENWFMDPEEWINEQM-ATSYEYQIRPCAE-------NVFQDLMNTFSELLVPYLLKKIE 447

  Fly   422 NPAT-------NWRSKDTAIYLVTSWASRGGTQKHGITQTSELVPLPEFCAQQIIPELERPNI-- 477
            |.|:       ::..|| |||         .:.:...:..||:|.......|..:||....||
Yeast   448 NDASKLSNSLDDFLRKD-AIY---------ASFQLSASAVSEMVDFDRLLIQVFLPEATNTNISG 502

  Fly   478 NEFPVLKAAAIKYVMVFRSI-LGPQVLASCLPQLIRHLPAESSVVHSYAACSVEKILSMRDASNA 541
            :|..:::......:..:.:: ...:..:.|.......|..|...|  ....:|:.:.:|.|..|
Yeast   503 DELRIIRRRVALIINEWSTVKCSEESKSLCYKLFTNFLTDEDDKV--VLLTTVQTVRTMVDDWN- 564

  Fly   542 IVFGPQILAPYTTELISGLFATLSLPGSGENE---YVMKAIMRSFSVLQSAAMPFMGV------A 597
              |......|:.||.:..|...: ||.....|   ||:..:  |..::|:..:....:      .
Yeast   565 --FNKDTFQPFLTENVHLLLRKI-LPSVSLTETRLYVLNTL--SDIIIQTKPLISRDLLVEILQI 624

  Fly   598 LPRLTEILTQVAKN---------------PSRPQFNHYLFETLALCIKIVCHADSSAVSSFEEAL 647
            :|.|.||.|..|..               .|....:|..::.....:.:.|...|.......|..
Yeast   625 IPNLWEIATNNASEAILANALLRLLRNLVSSLGSQSHLTWDIAIPVVALACDPSSMQYQLLSEDG 689

  Fly   648 FPVFQGILQ----------QDIVEFMPYV-------FQMLSVLLEMREGTGTIPEPYWALFPCLL 695
            :.::..:||          ...||.:|::       .::|..|||:.:.           :..:|
Yeast   690 YELWGMLLQNFSSHDQEFDDKFVELVPFLKYGIETHTEILPTLLEIIKS-----------YALIL 743

  Fly   696 SPALWDRTGNVTPLIRLISAF---IKQGSAQIQALGKLSGILGIFQKMIASKANDHEGFYLLQNL 757
            :|..:........:.:.:|.:   :::.|.|:        :|.|::.:|.|..:|:|.. |||
Yeast   744 NPVDFFSNNTFQDIFKQMSKYLLKLREDSFQL--------VLEIWEILILSNESDYENL-LLQ-- 797

  Fly   758 LSYYPPAEIQTNLRQIFGLLFQRLSLSKTP-KYLSGIII----------------FFSFY----V 801
             .:|...        :...||..:.|.:.| .||...||                |.:.|    .
Yeast   798 -KFYETG--------VLSALFDAIFLEEAPSSYLCSQIIQIIARISYVNPDALMTFLATYHDNLP 853

  Fly   802 IKFSGSQMAQLI------DEIQPNLFGMLLD-------RVFITEMGKIPKEQDRKMVAVGVTKLL 853
            .....::|.:.|      |:...::...||.       .:|..:..|:.......::..|:..:|
Yeast   854 TSNENARMPESIRKIVSKDQTYDSVVNKLLTGWIVCFRDIFDPKFKKVHILGISSLLRTGLVPIL 918

  Fly   854 TETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAEDPDAGYQVAFAQLTHAQPN 918
            ||...|     |:.|..:|..:.:......||....:|.....:|..|....|:.:.||  .:.|
Yeast   919 TEFSSI-----ASLWIEMLEEINETNRGDCEKYHLNDIVTEQSIAFHPLTAEQLRYHQL--CKNN 976

  Fly   919 QQDHLAEIKDARQFLATSLSKFAQARAG--EFSTLLSPLEPEYKQVLQKY 966
            ...|...:||   |::.|: ::.::..|  .:...|..:.|...:.||.:
Yeast   977 DPVHNISLKD---FISQSM-EYLESHLGVERYQEFLKTINPSLLENLQMF 1022

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	20/79 (25%)
		Cse1	159..528	CDD:285678	73/423 (17%)
		CAS_CSE1	530..966	CDD:281384	94/515 (18%)
KAP120	NP_015200.1	CSE1	8..1023	CDD:227944	203/1090 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810