Protein Alignment Cse1 and CSE1

DIOPT Version :10

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_011276.1
• Gene: CSE1 / 852612
• SGDID: S000003207
• Length: 960
• Species: Saccharomyces cerevisiae
• Alignment Length: 986
• Identity: 327/986 - (33%)
• Similarity: 531/986 - (53%)
• Gaps: 54/986 - (5%)

  Fly     6 ANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAIAFKNY 70
            ::|:.:|.:|.:::.|  :..:.:|:.|...|.|..:.:.||::|....:.::||:|||:.|||:
Yeast     2 SDLETVAKFLAESVIA--STAKTSERNLRQLETQDGFGLTLLHVIASTNLPLSTRLAGALFFKNF 64

  Fly    71 IKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQLID 135
            |||.|   :|.:|...:..::...||..||.||:..|..||.|:.:|:|.|...|||.:||.|:.
Yeast    65 IKRKW---VDENGNHLLPANNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDRWPTLLS 126

  Fly   136 EMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLTKV 200
            ::..|.::.|.....|||..|||:|||:|..|:|..|:.|||.|||....|..:||:...:....
Yeast   127 DLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITA 191

  Fly   201 HENNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVPSLRTADD-EDA 264
            :|||..:|.:::..|:::.|:::..|.||:||||||||...||.|.:.|:...|.|...|: |.|
Yeast   192 NENNKASLNILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHA 256

  Fly   265 GVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQFLSVVAD 329
            .||..:::.:.|.:.||..:|::.|.|.:.:|:...|.||...|...|||.|||.:|.||:.|..
Yeast   257 SVLIKVKSSIQELVQLYTTRYEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVTR 321

  Fly   330 RQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVK 394
            ...|..||.|...:..|.:::::||:.:|..|.|:|||.|.||||||:||||.||||||..|.:|
Yeast   322 IPKYFEIFNNESAMNNITEQIILPNVTLREEDVELFEDDPIEYIRRDLEGSDTDTRRRACTDFLK 386

  Fly   395 TLSINFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTSELVP 459
            .|....|..:..||..:::..:.:|..:|:.||:.||..|||.|:.|..|.....|::.|:.|:.
Yeast   387 ELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNWKFKDLYIYLFTALAINGNITNAGVSSTNNLLN 451

  Fly   460 LPEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSY 524
            :.:|..::|.|:|...||... :|:..||||:..||:.|....|...:|.|...|..:..||::|
Yeast   452 VVDFFTKEIAPDLTSNNIPHI-ILRVDAIKYIYTFRNQLTKAQLIELMPILATFLQTDEYVVYTY 515

  Fly   525 AACSVEKILSMRDA--SNAIVFGPQILAPYTTELISGLFATLSLPGS-----GENEYVMKAIMRS 582
            ||.::||||::|::  |.|.:|..:.::..|..|:..|.|.:...||     .|||::|::|.|.
Yeast   516 AAITIEKILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGSSPEKLAENEFLMRSIFRV 580

  Fly   583 FSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAVSSFEEAL 647
            ....:.:..|.....|.:..||:|.:|||||.|:|.||.||::.   .|:.:.....:....:::
Yeast   581 LQTSEDSIQPLFPQLLAQFIEIVTIMAKNPSNPRFTHYTFESIG---AILNYTQRQNLPLLVDSM 642

  Fly   648 FPVFQGILQQDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWALFPCLLSPALWDRTGNVTPLIRL 712
            .|.|..:..:||.||:|||||:::.::|.   :.||||....|...||:|.:|:..||:..:.||
Yeast   643 MPTFLTVFSEDIQEFIPYVFQIIAFVVEQ---SATIPESIKPLAQPLLAPNVWELKGNIPAVTRL 704

  Fly   713 ISAFIKQGSAQIQALGKLSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEIQTNLRQIFGLL 777
            :.:|||..|:   ....|..:|||||::|||||.:..||.||::::.......::..::||..||
Yeast   705 LKSFIKTDSS---IFPDLVPVLGIFQRLIASKAYEVHGFDLLEHIMLLIDMNRLRPYIKQIAVLL 766

  Fly   778 FQRLSLSKTPKYLSGIIIFFSFYVIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGKIPKEQDR 842
            .|||..|||.:|:..:.:||.....|.....:...|||:|..||..:.....||.:..|....||
Yeast   767 LQRLQNSKTERYVKKLTVFFGLISNKLGSDFLIHFIDEVQDGLFQQIWGNFIITTLPTIGNLLDR 831

  Fly   843 KMVAVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAE------DP 901
            |:..:||..::. ..:..|.:|.|.....::|:|             |...:..:|.      |.
Yeast   832 KIALIGVLNMVI-NGQFFQSKYPTLISSTMNSII-------------ETASSQSIANLKNDYVDL 882

  Fly   902 DAGYQVA-----FAQLTHAQPNQQDHLAEI---KDARQFLATSLSKFAQARAGEFSTLLSPLEPE 958
            |...:::     |::|........|.|.||   ...|.::|.:|:|: .|.:|  :|.|:.:.|:
Yeast   883 DNLEEISTFGSHFSKLVSISEKPFDPLPEIDVNNGVRLYVAEALNKY-NAISG--NTFLNTILPQ 944

  Fly   959 YKQVLQKYCDQ 969
            ..|..|...:|
Yeast   945 LTQENQVKLNQ 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:397745	27/75 (36%)
		Cse1	159..529	CDD:430038	139/370 (38%)
		CAS_CSE1	530..966	CDD:367469	135/456 (30%)
CSE1	NP_011276.1	CSE1	1..960	CDD:227944	327/986 (33%)