DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cse1 and AT1G26170

DIOPT Version :9

Sequence 1:	NP_523588.2	Gene:	Cse1 / 35016	FlyBaseID:	FBgn0022213	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_173942.2	Gene:	AT1G26170 / 839158	AraportID:	AT1G26170	Length:	1022	Species:	Arabidopsis thaliana

Alignment Length:	1160	Identity:	212/1160 - (18%)
Similarity:	389/1160 - (33%)	Gaps:	344/1160 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAIAF 67
            |.:.:.|.|.|.|..:|..:.|||..||..|....||..:...|..:.....:.:..|...|:..
plant     2 VVDQDQQWLLGCLSASLDPNQNVRSFAETSLNQASLQPGFGSALCRVAANKDLSLGLRQLAAVLL 66

  Fly    68 KNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQ 132
            |.:||::|..:.::.....:...::..|:..::..:..|...:...:|..:|.|..||:|::||:
plant    67 KQFIKKHWRENEEAFEYPLVSSEEKALIRGQLLGSLDDSHRKICTAISMDISSIATYDWPEEWPE 131

  Fly   133 LIDEMVERFAS-GDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKP-----LTDLL 191
            |:..:::..:. .:.|.::|.|:....|...                 ||....|     |...|
plant   132 LVPFLLKLISDPSNTNGVHGALRCLALLSGE-----------------LDDKEVPTLVPVLFPCL 179

  Fly   192 QATMQLTKVHEN--NAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVP 254
            .|.:...:.::.  ...||.::| |.:.|......:...:........:..||..|  .|..:.|
plant   180 HAVVSSPQSYDKYIRGKALTIVY-SCIYVLGAMSGVYKTETTTLVTPVLKVWMNQF--SLILEHP 241

  Fly   255 SLRTADDEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKT------------ 307
            ..|...|:.:     ||.:|.:  ||  .::.:.|...:|..:.|:...|..|
plant   242 VQREDPDDWS-----LRMEVLK--CL--NQFVQNFPSLIESELMAIMRPLWHTFESSLQVYLRSS 297

  Fly   308 ------SLHTKYDS---------LVSHALQFLS-VVADRQHYQSIFEN-PEILAQICDKVVIPNL 355
                  |...:|||         .|....:||| :|:.|:..::|..| .|::.|     .:..|
plant   298 IDGAEDSYDGRYDSDGEEKSLDTFVIQLFEFLSTIVSSRRLSKTIAGNVRELVYQ-----TVAFL 357

  Fly   356 DIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIFGQ---------Y 411
            .|.......:.....:::..:.|||       .:|.:...|.:   :::...||.         .
plant   358 QITEQQVHTWSMDVNQFVADEDEGS-------YSCRISGILLL---EEVINTFGSEGINAVVDAA 412

  Fly   412 LERLLTKYKENPATN---WRSKDTAIYLVTSWASRGGTQKHGITQTSEL----VPLPEFCAQQII 469
            .:|.....:||.|::   ||.::..::.:.|.:.:       :.:..:|    ..|.:| .:|:|
plant   413 GKRFQESQRENSASSLSWWRLREAVLFTLASLSDQ-------LVEAEDLRIDPANLAKF-IEQLI 469

  Fly   470 PELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSYAACSVEKILS 534
            .|......:|.|.|.|.....|..|.|::...:|...|...:|.:..:........||  ..:|.
plant   470 MEDTGIGYHECPFLYARIFTAVAKFSSVINAGILEHFLNAAVRAITMDVPPPVKVGAC--RALLQ 532

  Fly   535 MRDASNAIVFGPQILAPYTTELISGLFATLSLPGSGENEYVMKAIMRSFSVLQSAAMPFMGVALP 599
            :....|:.|..|||:         .||::
plant   533 LLPDMNSSVILPQIM---------NLFSS------------------------------------ 552

  Fly   600 RLTEILTQVAKNPSRPQFNHYLFETLALCIKIV---CHADSSAVSSFEEALFPV----------- 650
             ||::|.|...            |||.|.::.:   ..|...|.:|.|..:.||
plant   553 -LTDLLRQATD------------ETLVLVLETLQQAIKAGHEASASIESIISPVILNVWVAHISD 604

  Fly   651 -FQGILQQDIVE---------------FMPYVFQMLSVLLEMREGTGT----------------- 682
             |..|...|::|               .:|::..:|:...:..||..:
plant   605 PFMSIDVIDVLEAIKNSPGCLHPLTSRILPFIGPILNKPHQQPEGLASGSLDLLTMLLKGAPSDI 669

  Fly   683 IPEPYWALFPCLLSPALWDRT-GNVTPLIRLISAFIKQGSAQIQALGKLSGILGIFQKMIASKAN 746
            :...|...|..::...|.... |.:......::|||..|.   |.|...||..|...:.:....:
plant   670 VKTAYDFCFAAVIRIVLHSEDHGELQNATECLAAFISSGR---QELLTWSGDPGFTMRSLLDATS 731

  Fly   747 -----DHEGF-------YLLQNLLSYYPPAEIQTNLRQIFGLLFQRLSLSKTPKYLSGIIIFFSF 799
                 |.||.       |:||.:|  :.|:|:..:::.:...|.:||..::.......:::.|
plant   732 RLLNPDLEGSGSLFAGKYILQLIL--HLPSEMAPHVQDLVAALVRRLQSAEILALKGSLLLIF-- 792

  Fly   800 YVIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGKIPKEQDRKMVAVGVTKLLTETPEI----- 859
                      |:|:....||     :|: ||..:..||.:.........:|:...:..||
plant   793 ----------ARLVHMSYPN-----VDQ-FINLLVSIPADGHENSFTYVMTEWTKQQGEIQSAYQ 841

  Fly   860 -----------LQQQYATF----------------------------WPRLLHSLIDLFERPPEK 885
                       |..:::.|                            |     ::|.|    |.|
plant   842 IKVTTSALALLLSTRHSEFAKVNVPGSPIQSNGGITTRSKARSAPEQW-----TIIPL----PMK 897

  Fly   886 LMGL------EIGETAGVAEDPDAGYQVA-------------------FAQLTHAQ-------PN 918
            ::.|      ||.|.....||.|:.::..                   |::.|:.|       .|
plant   898 ILALLADTLIEIQEQVLSNEDEDSEWEEVHEGDAKAEKDLLRSAGTSQFSKPTYDQLEAMARFEN 962

  Fly   919 QQDH----------LAEIKDARQFLATSLSKFAQARAGEFSTLLSPLEPEYKQVL 963
            |.|.          |.||..| .::|..|.||:......|..|...|....:.|:
plant   963 QDDEVDDHLLGTDPLNEINLA-SYVADFLLKFSSEDRPLFDNLCQGLTNAQRNVI 1016

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	13/75 (17%)
		Cse1	159..528	CDD:285678	76/420 (18%)
		CAS_CSE1	530..966	CDD:281384	100/580 (17%)
AT1G26170	NP_173942.2	CSE1	20..860	CDD:227944	175/974 (18%)
		IBN_N	28..102	CDD:281761	13/73 (18%)
		HEAT repeat	460..497	CDD:293787	11/37 (30%)
		HEAT repeat	506..532	CDD:293787	4/27 (15%)
		HEAT repeat	543..572	CDD:293787	13/86 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810