DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cse1 and AT2G46520

DIOPT Version :9

Sequence 1:	NP_523588.2	Gene:	Cse1 / 35016	FlyBaseID:	FBgn0022213	Length:	975	Species:	Drosophila melanogaster
Sequence 2:	NP_182175.1	Gene:	AT2G46520 / 819263	AraportID:	AT2G46520	Length:	972	Species:	Arabidopsis thaliana

Alignment Length:	986	Identity:	367/986 - (37%)
Similarity:	594/986 - (60%)	Gaps:	25/986 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAI 65
            ||.....|..|:.....|||..|..||.||:.|.....|.||.:.:|.|:.:..:|..||.|.|:
plant     1 MEWNRETLVFLSQCFLNTLSPIPEPRRTAERALSDAADQANYGLAVLRLVAEPAIDEQTRHAAAV 65

  Fly    66 AFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKW 130
            .|||:::..|....|| |...|.:|::..||||||:|||.:...:|.|||:|:::|||:||||.|
plant    66 NFKNHLRSRWHPAGDS-GISPIVDSEKEQIKTLIVSLMLSASPRIQSQLSEALTVIGKHDFPKAW 129

  Fly   131 PQLIDEMVERF----ASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLL 191
            |.|:.|::...    .:||:..:||:|.||.|:||::.||:::.||:.::|:.||..|.|||::.
plant   130 PALLPELIANLQNAALAGDYVSVNGILGTASSIFKKFSYEYRTDALFVDLKYCLDNFAAPLTEIF 194

  Fly   192 QATMQLTKVHENNAGA---LKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADV 253
            ..|..|.....::.|:   ||.::.|..|...:|:|||.|||||||||::..|||.|.:.|:::.
plant   195 LKTSSLIDSAASSGGSPPILKPLFESQRLCCTIFYSLNFQDLPEFFEDHMKEWMGEFKKYLSSNY 259

  Fly   254 PSLRTADDEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVS 318
            |:|.:. :|...:::.|||.:||||..|.:|.:|||:.|:.:|.:.||.||...|.....|.|.:
plant   260 PALEST-EEGLTLVDDLRAAICENINHYIEKNEEEFQGFLNEFASVVWTLLRDVSKSPSRDQLAT 323

  Fly   319 HALQFLSVVADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDID 383
            .|::||:.|:...|: ::|....::.:||..:||||:.:|..||||||.:..|:||||:||||:|
plant   324 TAIKFLTSVSTSVHH-ALFAGDNVIKEICQSIVIPNVSLRVEDEEIFEMNYIEFIRRDMEGSDVD 387

  Fly   384 TRRRAACDLVKTLSINFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQK 448
            ||||.||:|:|.|:.|::.::..:....::|||:.:..||:.||:.||.|||||.|.:::   :.
plant   388 TRRRIACELLKGLATNYKTQVTEVVSLEIQRLLSSFSANPSANWKDKDCAIYLVVSLSTK---KA 449

  Fly   449 HGITQTSELVPLPEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRH 513
            .|.:.:::|:.:..|.|..|:|||:..::|.||:|||.::|::.:|||.:.........|:|:|.
plant   450 GGASVSTDLIDVQNFFANIILPELQSRDVNSFPMLKAGSLKFLTMFRSHIPKPFAMQLFPELVRF 514

  Fly   514 LPAESSVVHSYAACSVEKILSMRD---ASNAIVFGPQILAPYTTELISGLFATLSLPGSGENEYV 575
            |.|||:|||||||..:||:|.:::   ..|....|.  |:|:..:|::.||..|..|.|.||:|:
plant   515 LKAESNVVHSYAASCIEKLLLVKEEGARGNRYAAGD--LSPFLLQLMTNLFDALKFPESEENQYL 577

  Fly   576 MKAIMRSFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAV 640
            ||.|||...|...:| ...|..:..||.||::|.|||..|.|||||||::|:.::..|..|.|.:
plant   578 MKCIMRVLGVADISA-EVAGPCIGGLTSILSEVCKNPKNPIFNHYLFESVAVLVRRACERDISLI 641

  Fly   641 SSFEEALFPVFQGILQQDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWALFPCLLSPALWDRTGN 705
            |:||.:|||..|.||..||.||:||.||:|:.|:|:..  .|:...|..:|..||||..|.|:||
plant   642 SAFETSLFPSLQMILANDITEFLPYGFQLLAQLVELNR--PTLSPNYMQIFLLLLSPESWKRSGN 704

  Fly   706 VTPLIRLISAFIKQGSAQIQALGKLSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEIQTNL 770
            |..|:||:.||:::...::....:||.:||||:|::||.:.|.:|||:|..::.....:.|...:
plant   705 VPALVRLLQAFLQKAPHEVTQENRLSQVLGIFEKLVASPSTDEQGFYILNTIIENLDYSVIAPYM 769

  Fly   771 RQIFGLLFQRLSLSKTPKYLSGIIIFFSFYVIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGK 835
            :.::..||.|:...||.|:...::||.|.:::|...:.:.:.::.:|||:...:::..:|..:..
plant   770 KGVWSALFTRVQNKKTVKFQKSLVIFMSLFLVKHGQAYLVETMNTVQPNIITAIVEHFWIPNLKL 834

  Fly   836 IPKEQDRKMVAVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAED 900
            |....:.|:.||..|:|:.|||.:|....|..|.::|.|::.|..||.::.: |:..|...::|
plant   835 IMGSMEVKLTAVAATRLICETPALLDPSAAKLWGKMLDSIVTLVSRPEQERV-LDEPEMPEISE- 897

  Fly   901 PDAGYQVAFAQLTHAQPNQQDHLAEIKDARQFLATSLSKFAQARAGEFSTLLSP-LEPEYKQVLQ 964
             :.||..||.:|.:|...::|.|.:|||.:|||..|:|:.:.|..|.:..::.. ||...:..|.
plant   898 -NVGYTAAFVKLHNAGKKEEDPLKDIKDPKQFLVASVSRLSSASPGRYPQIIGENLEQANQTALI 961

  Fly   965 KYCDQAGVRIA 975
            :.|:.....||
plant   962 QLCNAYNCGIA 972

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	30/75 (40%)
		Cse1	159..528	CDD:285678	148/371 (40%)
		CAS_CSE1	530..966	CDD:281384	151/439 (34%)
AT2G46520	NP_182175.1	IBN_N	29..104	CDD:281761	30/75 (40%)
		Cse1	162..529	CDD:285678	148/371 (40%)
		CAS_CSE1	531..963	CDD:281384	151/439 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	291	1.000	Domainoid score	I360
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1006
Inparanoid	1	1.050	671	1.000	Inparanoid score	I151
OMA	1	1.010	-	-		QHG53855
OrthoDB	1	1.010	-	-		D1248958at2759
OrthoFinder	1	1.000	-	-		FOG0004998
OrthoInspector	1	1.000	-	-		oto3228
orthoMCL	1	0.900	-	-		OOG6_101888
Panther	1	1.100	-	-	LDO	PTHR10997
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3532
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840