Protein Alignment Cse1 and ipo11

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001039123.1
• Gene: ipo11 / 733946
• XenbaseID: XB-GENE-494941
• Length: 975
• Species: Xenopus tropicalis
• Alignment Length: 1132
• Identity: 233/1132 - (20%)
• Similarity: 390/1132 - (34%)
• Gaps: 327/1132 - (28%)

  Fly     1 MEVTEAN---LQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVA 62
            |::..|:   ||:|.    |..|.|..|.:|||:.|:..|.|..:..:|||:.....:|:..|..
 Frog     1 MDLNSASGVVLQVLT----QASSQDSAVLKPAEEQLKQWETQPGFYTVLLNIFTNHSLDVNVRWL 61

  Fly    63 GAIAFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPV-ALQKQLSDAVSIIGKYDF 126
            ..:.|||.|.|.|.    ...|..:.|.::.|::..::| ..:.|| .:..|::..::.:.:.|.
 Frog    62 AVLYFKNGIDRYWR----RVAPHALSEEEKATLRAGLIT-NFNEPVNQIATQIAVLIAKVARLDC 121

  Fly   127 PKKWPQLIDEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLL 191
            ||:||:||..::|.....|                                           ||.
 Frog   122 PKQWPELIPTLIESVKIQD-------------------------------------------DLR 143

  Fly   192 QATMQLTKVHENNAGALKVIYGSLVLVNKVFFSLNSQDL-PEFFEDNINTW---MGAFIQQL--- 249
            |....||..|     ..|.:....:..::..|    ||| .|.:....:.|   ...|:||:
 Frog   144 QHRALLTFYH-----VTKTLSSKRLAADRKLF----QDLASEIYSFTCSLWNHHTDTFLQQICSG 199

  Fly   250 --AADVPSL-RTADDEDA-------GVLE-HLRAQV----------------------CENICLY 281
              .|.:.|| ||......       |.|| |..|.|                      .||:|
 Frog   200 GETAAINSLERTLLSLKVLRKLTVHGFLEPHQNADVTGFLLAVFVRLKQFLDCSRNIGAENVC-- 262

  Fly   282 AKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQF-LSVVADRQHYQSIFENPEILAQ 345
                .|..:..:..|...:.:.|.:..:  .:..|:..:|:| :|.|........:||...:...
 Frog   263 ----RERLEKIIILFTKVLLDFLDQHPI--SFIPLIQRSLEFAVSYVFTEAGDGIVFERFIVQCM 321

  Fly   346 ICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIF-- 408
            ...|:::......||..  ||||..|                         :||..|.....|
 Frog   322 SLIKMIVKEDSYIPSKN--FEDSKPE-------------------------TINAHQIKLSFFTH 359

  Fly   409 ---GQYLERLLTKY---KENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTSELVPLPEF--CA 465
               .:...||:|.|   .:.....| .:|...:.|..  :.|.:.|:.:...||::.:..|  .:
 Frog   360 QTLTEICRRLVTHYFILSDEELAMW-EEDPEGFAVEE--TGGDSWKYSLRPCSEVLFIDIFHEYS 421

  Fly   466 QQIIPELERPNINEFPVLKAAA---------IKYVMVFRSI-LGPQVLASCL-------PQLIRH 513
            :.:.|.|    :|....:|...         ||.. |:.:: |....|..|:       .||:
 Frog   422 ETLTPVL----LNMVDTIKGPTCVEDLNTLRIKET-VYNAVGLAAYELFDCIDFDEWFQSQLL-- 479

  Fly   514 LPAESSVVHSYAACSVEKILSMRDASNAIVFGPQILAPYTTELISGLFATLSLPGSGENEYVMKA 578
              .|..|.|........:::.:.....::.|... |.|...|.|..|.....|....|....:|.
 Frog   480 --GELQVAHDRYKLLRRRVIWLIGQWISVKFKAD-LRPLLYEAILSLLQDPDLVVRIETATTLKL 541

  Fly   579 IMRSFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAVSSF 643
            .:..|.......:|::......|.::|.||.:..|:.|               |.|..|..:...
 Frog   542 TVDDFEFRTEQFLPYLETTFSLLFQLLQQVTECDSKMQ---------------VLHVLSCVIERV 591

  Fly   644 EEALFPVFQGILQQDIVEFMPYVFQ-----------MLSVLLEMREGTGTIPEPYWALFPCLL-- 695
            ...:.| |.|.|    |:::|.:::           :||.|:.:.:|.|...|   .|:|.||
 Frog   592 NMQIRP-FVGCL----VQYLPLLWKQSEEHNMLRCAILSTLVHLIKGLGGSSE---NLYPFLLPV 648

  Fly   696 --------SP----------ALW----DRTGNVTP-LIR---------------------LISAF 716
                    .|          .||    :...:||| |:|                     :|:|:
 Frog   649 IQLSTDVSQPPHVYLLEDGLELWLVTLENCSSVTPELLRIFHNMAALLELSSENLLICFKIINAY 713

  Fly   717 IKQGSA---QIQALGKLSGILGIFQKMIASKANDHEG----FYLLQNLLSYYP---PAEIQTNLR 771
            |...|:   ||.|.......|.:.:.:      .:||    ..:::|:|...|   |...|..|.
 Frog   714 IFSSSSEFLQIYAANLCQAFLELLRDI------TNEGQVQVLKVVENVLKVNPAVGPQMFQALLP 772

  Fly   772 QIFGLLFQRLSLSKTPKYLS---GII--------IFFSFYVIKFSGSQMAQLIDEIQPNLFGMLL 825
            .:|..:.:.   .|.|..:|   ||:        ..||..:.:.|.....: .|:|..||..|.:
 Frog   773 PVFRGIIEG---EKYPVVMSTYLGILGRVLLQNQCCFSSLLYQLSQEYNCE-PDQILGNLIEMWV 833

  Fly   826 DRVFITEMGKIPKEQDRKMVAVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPE-----K 885
            ||     |..|.:.:.||:.|:.:..||.....|:|.::.......:.||.|:....||     .
 Frog   834 DR-----MDNITQPERRKLSALALLSLLPSANSIIQDKFCGIINVCVESLHDVMTEDPETSTYKD 893

  Fly   886 LMGLEIGETAGVAEDPDAGYQVAFAQLTHAQPNQQD---HLAEIKD------ARQFLATSLSKFA 941
            .|.:...|...|.||.:             .|.:||   .:..:||      .:||:...| |..
 Frog   894 CMLMSHLEDPQVIEDEE-------------PPTEQDKRKKMLALKDPVHAVSLQQFVYEKL-KAQ 944

  Fly   942 QARAGE--FSTLLSPLEPEYKQVLQKY 966
            |...||  |.:|:..::.|....||::
 Frog   945 QELLGEEGFRSLMETVDTEIVTQLQEF 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	20/75 (27%)
		Cse1	159..528	CDD:285678	79/436 (18%)
		CAS_CSE1	530..966	CDD:281384	112/529 (21%)
ipo11	NP_001039123.1	CSE1	10..>681	CDD:227944	158/802 (20%)
		IBN_N	28..100	CDD:281761	20/76 (26%)
		HEAT repeat	515..545	CDD:293787	6/29 (21%)
		HEAT repeat	552..586	CDD:293787	9/48 (19%)
		HEAT repeat	599..630	CDD:293787	7/34 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910