Protein Alignment Cse1 and ipo11

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_005167213.1
• Gene: ipo11 / 432373
• ZFINID: ZDB-GENE-040711-1
• Length: 975
• Species: Danio rerio
• Alignment Length: 1081
• Identity: 209/1081 - (19%)
• Similarity: 407/1081 - (37%)
• Gaps: 225/1081 - (20%)

  Fly     1 MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAI 65
            |::..|:..:|.. |.|..|.|..|.:|||:.|...|.|..:..:||::.:...:|:..|....:
Zfish     1 MDIQSASSVVLQA-LTQATSQDTAVLKPAEEQLRQWETQPGFYSVLLSIFNNHLLDVNVRWLAVL 64

  Fly    66 AFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPV-ALQKQLSDAVSIIGKYDFPKK 129
            .|||.|.|.|.    ...|..:.|.::::::..::| ..:.|| .:..|::..::.:.:.|.|::
Zfish    65 YFKNGIDRYWR----RVAPHALSEEEKSSLRAGLIT-NFNEPVNQIATQIAVLIAKVARLDCPRQ 124

  Fly   130 WPQLIDEMVERFASGDF------------------------------NVINGVLQTAHSLFKRYR 164
            ||:||..::|.....|.                              ::.:.:...|.||:..:.
Zfish   125 WPELIPILLESVKVQDSLQQHRALLTFYHVTKTLASKRLATDRRLFQDLASSIYSFACSLWNHHT 189

  Fly   165 YEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLTKVH-----ENN---AGALKVIY--------- 212
            ..|..|....:.:..|..:.:.|.. |:...:|| ||     :||   .|.|..::
Zfish   190 DSFLQQIYSGDQQTALSSLERTLLS-LKVLRKLT-VHGFVDPQNNMEVMGFLNAVFERLKQFLEC 252

  Fly   213 ------GS---------LVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVPSLRTADDE 262
                  ||         ::|..||        |.:|.|.:...::....:.|...|..:.|...|
Zfish   253 CRQVGPGSPCREKLEKTIILFTKV--------LLDFLEYHPCPFIPLIQRSLEFAVSYVFTEAGE 309

  Fly   263 DAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQFLSVV 327
            .. |.|....| |.|:.....|.| .:||             .|....:|.:||.:|.:
Zfish   310 GV-VFERFIVQ-CMNLIKMIVKND-AYKP-------------AKNIEDSKPESLEAHRI------ 352

  Fly   328 ADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDL 392
                  ::.|...:.|.:|..::|.....:...:..::|:.||.:...:..|.......|.:.:
Zfish   353 ------KTAFFTHQTLTEIGRRLVSKYFLLTEEELTMWEEDPESFAVEETGGDSWKYSLRPSTE- 410

  Fly   393 VKTLSI--NFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTS 455
            |..|.|  |:.|.:..:..:.::.|..............|| |:|.....|:         .:..
Zfish   411 VLFLDIFHNYSQTLTPVLLEMVQNLQGPSNVEDPVQMLMKD-AVYNAVGLAA---------YELF 465

  Fly   456 ELVPLPEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSV 520
            :.|...::...|::.||:..: |.:.:::...|..:..:.|:.....|...|.::|..|..:..:
Zfish   466 DNVDFDQWFKNQLLGELQVSH-NRYKLIRRRVIWLIGQWISVKFKPELRPLLYEVILSLMQDPDL 529

  Fly   521 VHSYAACSVEKILSMRDASNAIVFGPQILAPYTTELISGLFATLSLPGSGENE----YVMKAIMR 581
            |     ..:|...:::.|.:...|..:...||...:.|.||..|......:.:    :|:..::.
Zfish   530 V-----VRIETATTLKLAVDDFEFRTEQFLPYLESIFSLLFQLLQQVNECDTKMQVLHVISCVIE 589

  Fly   582 SFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIV--CHADSSAVSSFE 644
            ..|:   ...|::|..:..|..:..|      ..:.|......|...|.:|  ..|:|..:..|
Zfish   590 RVSI---QIRPYVGCLVQYLPLLWKQ------SEEHNMLRCAILTTLIHLVQGLGAESKNLYPF- 644

  Fly   645 EALFPVFQGILQQDIVEFMPYVFQM---LSVLLEMREGTGTIPEPYWALFPCLLSPALWDRTGNV 706
              |.||.|  |..|:.: .|:|:.:   |.:.|...|.:..|......:|. .:||.|...:.||
Zfish   645 --LLPVIQ--LSTDVSQ-PPHVYLLEDGLELWLVTLENSPAITPELLRIFQ-NMSPLLELSSENV 703

  Fly   707 TPLIRLISAFIKQGSAQI-----QALGKLSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEI 766
            ....::|:|:|...:...     :||.:      .|.::::...|:.:        :......||
Zfish   704 RTCFQIINAYIYLSATDFLQNYAEALCR------SFCELLSDITNEGQ--------VQVLKVVEI 754

  Fly   767 QTNLRQIFGL-LFQRLSLSKTPKYLSGII------IFFSFY-------VIKFSG------SQMAQ 811
            ...:..|.|. :||.|    .|..:.||:      :..|.|       :::.||      :|||.
Zfish   755 AIKVSPILGSHMFQPL----LPSVIRGIVEGERYPVVMSTYLGVTGRILLQNSGFFTSLLTQMAV 815

  Fly   812 LIDEIQPNLFGMLLDRVFITEMGKIPKEQDRKMVAVGVTKLLTETPEILQQQYATFWPRLLHSLI 876
            ..::....|.|.::: :::..|..|.:.:.||:.|:.:..||.....::|.::.......:.:|.
Zfish   816 EFNQEADQLLGSMIE-MWVDRMDNITQPERRKLSALALLSLLPSDNSVIQDKFCGIINISVEALH 879

  Fly   877 DLFERPPE-----KLMGLEIGETAGVAEDPDAGYQVAFAQLTHAQPNQQD---HLAEIKD----- 928
            |:....||     ..|.:...|...:.:|.:             .|.:||   .|..::|
Zfish   880 DVMTEDPETATFKDCMLMSHFEEPKLTDDEE-------------PPTEQDKRRKLLALEDPVHSV 931

  Fly   929 -ARQFLATSLSKFAQARAGE--FSTLLSPLEPEYKQVLQKY 966
             .:||:...| |..|...|:  |..|:..::.|..:.||::
Zfish   932 SLQQFVYEKL-KAQQMLMGDQGFQALMETVDTEIVRQLQEF 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	18/75 (24%)
		Cse1	159..528	CDD:285678	72/402 (18%)
		CAS_CSE1	530..966	CDD:281384	97/485 (20%)
ipo11	XP_005167213.1	CSE1	10..>760	CDD:227944	159/840 (19%)
		IBN_N	28..100	CDD:281761	18/76 (24%)
		HEAT repeat	515..545	CDD:293787	6/34 (18%)
		HEAT repeat	559..586	CDD:293787	5/26 (19%)
		HEAT repeat	599..630	CDD:293787	6/36 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000