Protein Alignment Cse1 and Ipo11

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_038959425.1
• Gene: Ipo11 / 310056
• RGDID: 1311133
• Length: 985
• Species: Rattus norvegicus
• Alignment Length: 1119
• Identity: 214/1119 - (19%)
• Similarity: 421/1119 - (37%)
• Gaps: 291/1119 - (26%)

  Fly     1 MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAI 65
            |::..|:..:|. .|.|..|.|..|.:|||:.|:..|.:|.:..:|||:.....:|:..|....:
  Rat     1 MDLNSASSVVLQ-VLTQATSQDTAVLKPAEEQLKQWETRQVFYSVLLNIFTNHTLDINVRWLAVL 64

  Fly    66 AFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSI----IGKYDF 126
            .||:.|.|.|.    ...|..:.|..::|::..::| ..:.|:   .|::..:::    :.:.|.
  Rat    65 YFKHGIDRYWR----RVAPHALSEEXKSTLRAGLIT-NFNEPI---NQIATLIAVLIAKVARLDC 121

  Fly   127 PKKWPQLIDEMVERFASGD------------------------------FNVINGVLQTAHSLFK 161
            |::||:||..:||.....|                              :::.:|:...|.||:.
  Rat   122 PRQWPELIPTLVESVXVQDDLRQHRALLTFYHVTKTLASKRLDCXQKAIYDLASGIYNFACSLWN 186

  Fly   162 RYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLT-----KVHENN--AGALKVIYGSLVLVN 219
            .:...|..|........||..:.:.|.. |:...:||     :.|:|.  .|.|..|:
  Rat   187 HHTDTFLQQVSSGNEAAVLSSLERTLLS-LKVLRKLTVNGFVEPHKNMEVMGFLHGIF------- 243

  Fly   220 KVFFSLNSQDLPEFFE-------DNI--------------NTWMGAFIQQLAADVPSLRTADDED 263
                    :.|.:|.|       ||:              ...:|...|...:..|.::.:.:..
  Rat   244 --------ERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVVTLGLLDQPPISFTPLIQRSLEFS 300

  Fly   264 AGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLH--TKY------DSLVSHA 320
               :.::..:|.|.:         .|:.|:.|.:..: :::||...:  :|:      ::|.:|.
  Rat   301 ---VSYVFTEVGEGV---------TFERFIVQCMNLI-KMIVKNYAYKPSKFFPDSSPETLEAHK 352

  Fly   321 LQFLSVVADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTR 385
            ::           .:.|..| .|.:||.::|.....:...:..::|:.||.:   .:|.:..|:.
  Rat   353 IK-----------MAFFTYP-TLTEICRRLVSHYFLLTEEELTMWEEDPEGF---TVEETGGDSW 402

  Fly   386 RRAACDLVKTLSINFEQKIFGIFGQYLERLLTKYKE--NPATNWRS------KDTAIYLVTSWAS 442
            :.:.....:.|.|:    ||..:.|.|..:|.:..:  ...||...      || |:|.....|:
  Rat   403 KYSLRPCTEVLFID----IFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKD-AVYNAVGLAA 462

  Fly   443 RGGTQKHGITQTSELVPLPEFCAQQIIPELERPNINEFPVLKAAAI----KYVMV-FRSILGPQV 502
                     .:..:.|...::...|::|||:..: |.:..|:...|    :::.| |:|.|.|:
  Rat   463 ---------FELFDSVDFDQWFKTQLLPELQVSH-NRYKPLRRRVIWLIGQWISVKFKSDLRPR- 516

  Fly   503 LASCLPQLIRHLPAESSVVHSYAACSVEKILSMRDASNAIVFGPQILAPYTTELISGLFATLSLP 567
                |.:.|.:|..:..:|     ..:|...:::...:...|......||...:.:.||..|...
  Rat   517 ----LYEAICNLLQDQDLV-----VRIETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQV 572

  Fly   568 GSGENE----YVMKAIMRSFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALC 628
            ...:.:    :|:..::...::   ...|::|..:..|..:..|      ..:.|......|...
  Rat   573 TECDTKMHVLHVLSCVIERVNI---QIRPYVGCLVQYLPLLWKQ------SEEHNMLRCAILTTL 628

  Fly   629 IKIV--CHADSSAVSSFEEALFPVFQGILQQDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWAL- 690
            |.:|  ..|||..:..|   |.||.|  |..|:.: .|:|: :|...||:           |.:
  Rat   629 IHLVQGLGADSKNLYPF---LLPVIQ--LSTDVSQ-PPHVY-LLEDGLEL-----------WLVT 675

  Fly   691 ---FPCLLSPALWDRTGNVTPLIRLISAFI--KQGSAQIQALGKL-----------------SGI 733
               .|| ::|.|.....|::||:.|.|:.:  :..|..::...|:                 :|:
  Rat   676 LENSPC-VTPELLRIFQNMSPLLELPSSCLANELSSENLRTCFKIINGYIFLSSTEFLQTYAAGL 739

  Fly   734 LGIFQKMIASKANDHEGFYL--LQNLLSYYPPAEIQTNLRQIFGLLFQRLSLSKTPKYLSGII-- 794
            ...|.:::.....:.:...|  ::|.|...|....|         :|||:    .|....|:|
  Rat   740 CQSFYELLPEITTEGQVQVLKVVENTLKVNPVLGPQ---------MFQRI----LPYVFRGVIEG 791

  Fly   795 ----IFFSFY-----------------VIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGKIPK 838
                :..|.|                 ::...|.:..|.:|::..|:..|.:||     |..|.:
  Rat   792 ERYPVVMSIYLAVMGRVLLQNASFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDR-----MDNITQ 851

  Fly   839 EQDRKMVAVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPE-----KLMGLEIGETAGVA 898
            .:.:|:.|:.:..||.....::|.::.......:.:|.|:....||     ..|.:...|...|.
  Rat   852 PERKKLSALALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSHHEEPKVT 916

  Fly   899 EDPDAGYQVAFAQLTHAQPNQQD---HLAEIKD------ARQFLATSLSKFAQARAGE--FSTLL 952
            ||.:             .|.:||   .:..:||      .:||:...| |..|...||  |.:|:
  Rat   917 EDEE-------------PPTEQDKRKKMLALKDPVHTVSLQQFIYEKL-KAQQEILGEQGFQSLM 967

  Fly   953 SPLEPEYKQVLQKY 966
            ..::.|....||::
  Rat   968 ETVDTEIVTQLQEF 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	19/75 (25%)
		Cse1	159..528	CDD:285678	74/417 (18%)
		CAS_CSE1	530..966	CDD:281384	98/505 (19%)
Ipo11	XP_038959425.1	CSE1	10..982	CDD:227944	212/1110 (19%)
		HEAT repeat	427..460	CDD:293787	7/33 (21%)
		HEAT repeat	479..506	CDD:293787	6/27 (22%)
		HEAT repeat	516..546	CDD:293787	5/39 (13%)
		HEAT repeat	553..587	CDD:293787	6/33 (18%)
		HEAT repeat	600..631	CDD:293787	6/36 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910