Protein Alignment Cse1 and Ipo9

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_722469.1
• Gene: Ipo9 / 226432
• MGIID: 1918944
• Length: 1040
• Species: Mus musculus
• Alignment Length: 1095
• Identity: 206/1095 - (18%)
• Similarity: 394/1095 - (35%)
• Gaps: 258/1095 - (23%)

  Fly     5 EANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAIAFKN 69
            ||.:..|.|    .||....||..||:.::..|:.:.:.:.|..|....|..:..|...::..|.
Mouse    23 EALVDTLTG----ILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQ 83

  Fly    70 YIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKWPQLI 134
            |::.:|.|..:...|....|..:..|:.|:...:..|...::..::.|||.|..:|:|:.||||.
Mouse    84 YVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLF 148

  Fly   135 DEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFV----LDRMAKPLT------- 188
            :.::|...|||.|.::|.:        |...||..:....::..|    |..|.|..|
Mouse   149 NLLMEMLVSGDLNAVHGAM--------RVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGI 205

  Fly   189 --------DLLQATMQLTKVHENNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAF 245
                    ........:..:.|...||.||:...:|              .:|.|        ||
Mouse   206 RTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVV--------------QQFTE--------AF 248

  Fly   246 IQQLAADVPSLRTADDEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELL------ 304
            :|  |..:|...|:|       ...:.:|.:.:....|.:.:.....|:|.:..||..|
Mouse   249 VQ--ALQMPDGPTSD-------SGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAF 304

  Fly   305 -VKTSL-HTK--------------YDSLVSHALQFLSVVADRQHYQSIFEN--PEILAQICDKVV 351
             |:|.: :|:              :::||....:|:..:.:...::|..:.  ||::..|
Mouse   305 YVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYI----- 364

  Fly   352 IPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIFGQYLERLL 416
            |..:.|.....:::..:|::::..:.:.:...|.|.||.||:..::.:|:.:..........|.|
Mouse   365 ILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAVALATAATRHL 429

  Fly   417 TKYKENPATN----WRSKDTAIY-------LVTSWASRGGT--QKHGITQTSELVPL-------- 460
            .:.::..|:.    |:..:..:.       ::|.....|..  ..||......||.|
Mouse   430 QEAEQTKASGTEHWWKIHEACMLALGSVKSIITDSVKNGRIHFDMHGFLTNVILVDLNLSASPFL 494

  Fly   461 ----------------PEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSIL----GPQVLAS 505
                            ||...|.:...:...:..:.|.::.:|::.:..:...|    ...||..
Mouse   495 LGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQP 559

  Fly   506 CLPQLIR---HLPAESS------VVHSYA-ACSVEKILSMRDASNAIVFGPQILAPYTTE----- 555
            .||.::.   ||.|:.|      |:.:.. .|:|:...:....:....|...|...|:.:
Mouse   560 FLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASVENKICPFTIAIFLKYSNDPVVAS 624

  Fly   556 LISGLFATLSLPGSGENEYVMKAIMRSFSVLQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHY 620
            |...:|..||...:.:....|:.|....|::|:.|............:|||.|.:| ::|..:..
Mouse   625 LAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRN-TKPPLSQL 688

  Fly   621 L----FETLALCIKIVCHADSSAVSSFEEALFPVFQGILQQDIVEF--------MPYVFQMLSVL 673
            |    |..:|.|   ..|.|.:|...........:..:..:.:.::        :.||.|::|.|
Mouse   689 LICQAFPAVAQC---TLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQL 750

  Fly   674 LEMREGTGTIPEPYWALFPCLLSPALWDRTGNVTPLIRLISAFIKQGSAQIQALGK-LSGILGIF 737
            |:.|....|      |.|                 :.||:|..|.:...:   ||: |..||
Mouse   751 LDPRTSEFT------AAF-----------------VGRLVSTLISKAGRE---LGENLDQIL--- 786

  Fly   738 QKMIASKANDHEGFYLLQNLLSYYPPAEIQTNLRQIFGLLFQRLSLSKTP-------KYLSGIII 795
             :.|.||....|...::|:|:..:... :.|.|..:...|......:..|       ::.|...:
Mouse   787 -RAILSKMQQAETLSVMQSLIMVFAHL-VHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHL 849

  Fly   796 FFSFYVIKFSGSQMAQLI------DEIQPNLFGMLLDRVFITEMG--------KIPKEQDRKMVA 846
            |:..|..|.|...:.:|:      |:.:.....:..:.::..:.|        |.|:......:.
Mouse   850 FYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLL 914

  Fly   847 VGVTKL-LTETPEILQ-----QQYATFWPRLLHSLIDLFERPPEK------LMGLEIGETAGVA- 898
            |.:.|| :.|...:::     |.....|.:  ....|::|...|:      |.|..:.:....:
Mouse   915 VKILKLIINELSNVMEANAARQATPAEWNQ--DDSNDMWEDQEEEEEEEDGLAGQLLSDILATSK 977

  Fly   899 -----------EDPDAGYQVAFAQLTHAQPNQQDHLAEIKDARQFLATSLSKFAQ 942
                       :||||               .:|.|.:| |.:.:|...|.:|||
Mouse   978 YEEDYYEDDEEDDPDA---------------LKDPLYQI-DLQAYLTDFLCQFAQ 1016

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	15/75 (20%)
		Cse1	159..528	CDD:285678	76/462 (16%)
		CAS_CSE1	530..966	CDD:281384	88/476 (18%)
Ipo9	NP_722469.1	SXM1	22..900	CDD:227943	180/959 (19%)
		IBN_N	43..117	CDD:197981	15/73 (21%)
		HEAT repeat	420..459	CDD:293787	4/38 (11%)
		HEAT repeat	469..508	CDD:293787	5/38 (13%)
		HEAT repeat	516..543	CDD:293787	3/26 (12%)
		HEAT repeat	561..587	CDD:293787	7/25 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810