Protein Alignment Cse1 and AgaP_AGAP010711

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_311424.1
• Gene: AgaP_AGAP010711 / 1272510
• VectorBaseID: AGAP010711
• Length: 972
• Species: Anopheles gambiae
• Alignment Length: 975
• Identity: 619/975 - (63%)
• Similarity: 778/975 - (79%)
• Gaps: 3/975 - (0%)

  Fly     1 MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAI 65
            ||:.|.|.:.||.||||||:.||.||||||:.:||.|:.||||:|.|:|||:.|:|||.|||.||
Mosquito     1 MEINENNFERLASYLQQTLNPDPEVRRPAERFIESIEVSQNYPLLCLHLIDRPQVDMTIRVAAAI 65

  Fly    66 AFKNYIKRNWAAHLDSDGPDRIHESDRNTIKTLIVTLMLHSPVALQKQLSDAVSIIGKYDFPKKW 130
            ||||:|||||..|||:|||:::.||||..||.|||.:||.||.|:|||||||||||||||||.||
Mosquito    66 AFKNFIKRNWGFHLDNDGPNKVSESDRTGIKGLIVPMMLKSPAAIQKQLSDAVSIIGKYDFPTKW 130

  Fly   131 PQLIDEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATM 195
            |:|:|||:|:||:|||::||||||||||||||||||||||.||||||:|||:||||||||||||:
Mosquito   131 PELMDEMIEKFATGDFHIINGVLQTAHSLFKRYRYEFKSQELWEEIKYVLDKMAKPLTDLLQATL 195

  Fly   196 QLTKVHENNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWMGAFIQQLAADVPSLRTAD 260
            .|.:.|..|..||.|||.|||||.||||||||||||||||||:.|||.||...|..|||.|:|.|
Mosquito   196 GLAEAHAGNKEALSVIYNSLVLVCKVFFSLNSQDLPEFFEDNMETWMKAFHGLLTVDVPCLKTDD 260

  Fly   261 DEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELLVKTSLHTKYDSLVSHALQFLS 325
            |||||||||||:|:|||:|:||.||||||.|:|.||||||||||||:.:|||||:|||:||:|||
Mosquito   261 DEDAGVLEHLRSQICENLCMYALKYDEEFSPYMPQFVTAVWELLVKSHIHTKYDALVSNALRFLS 325

  Fly   326 VVADRQHYQSIFENPEILAQICDKVVIPNLDIRPSDEEIFEDSPEEYIRRDIEGSDIDTRRRAAC 390
            .||:|.||:.:||:|.:||.||:||:|||:|.|.||||:|||:|||||||||||||::|||||||
Mosquito   326 TVAERTHYRHLFEDPNVLASICEKVIIPNMDFRVSDEELFEDNPEEYIRRDIEGSDVETRRRAAC 390

  Fly   391 DLVKTLSINFEQKIFGIFGQYLERLLTKYKENPATNWRSKDTAIYLVTSWASRGGTQKHGITQTS 455
            ||||:|...||.||..||||||:.||.||.||||.||::||||||||||.||:|.|||.|:||||
Mosquito   391 DLVKSLLQKFEAKIVEIFGQYLQVLLAKYAENPAANWKAKDTAIYLVTSMASKGQTQKLGVTQTS 455

  Fly   456 ELVPLPEFCAQQIIPELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSV 520
            ||||||:|..|||||||||.::|:.|||||.|:|::|.||:|||||::.:.:|.:.:||.|.|.|
Mosquito   456 ELVPLPQFTQQQIIPELERADVNQLPVLKADALKFIMTFRTILGPQIIVATMPLVSKHLGAASVV 520

  Fly   521 VHSYAACSVEKILSMRDASNAIVFGPQILAPYTTELISGLFATLSLPGSGENEYVMKAIMRSFSV 585
            ||:||||:::|||:||......:...:||:|.:.|||:||||.:::.||.||||:||.|||..:.
Mosquito   521 VHTYAACAIDKILTMRGPDKQPIVTKEILSPLSAELIAGLFAAITVQGSNENEYIMKCIMRVLNT 585

  Fly   586 LQSAAMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFETLALCIKIVCHADSSAVSSFEEALFPV 650
            ||.|::|||.|.|||||:||:.||||||:|.|||||||||:|.:|:||.||.:||||||||||||
Mosquito   586 LQEASLPFMIVVLPRLTDILSTVAKNPSKPHFNHYLFETLSLSVKLVCKADPNAVSSFEEALFPV 650

  Fly   651 FQGILQQDIVEFMPYVFQMLSVLLEMREGTGTIPEPYWALFPCLLSPALWDRTGNVTPLIRLISA 715
            ||||||||::|||||||||||:.||:|||...||:.|.|||||||:||||:|.|||||||||:.|
Mosquito   651 FQGILQQDVLEFMPYVFQMLSLFLEIREGKSNIPDTYLALFPCLLTPALWERPGNVTPLIRLLCA 715

  Fly   716 FIKQGSAQIQALGKLSGILGIFQKMIASKANDHEGFYLLQNLLSYYPPAEIQTNLRQIFGLLFQR 780
            |::|.||||.|..||:|:||:||||||||.|||||||||||||.|||..|:..::||||.|||||
Mosquito   716 FVRQASAQISADDKLNGVLGVFQKMIASKNNDHEGFYLLQNLLLYYPAEELGRSMRQIFSLLFQR 780

  Fly   781 LSLSKTPKYLSGIIIFFSFYVIKFSGSQMAQLIDEIQPNLFGMLLDRVFITEMGKIPKEQDRKMV 845
            ||.|||.|::...|:|...|..:.....:.|:|:.||..:|||:::||||.::.|:..|.::|:|
Mosquito   781 LSSSKTTKFVRSFIVFLCLYTARVGPQALIQMIESIQAQMFGMVVERVFIPDINKVSGELEQKIV 845

  Fly   846 AVGVTKLLTETPEILQQQYATFWPRLLHSLIDLFERPPEKLMGLEIGETAGVAEDPDAGYQVAFA 910
            :||:||||.|.||:|.:.|..|||:||.:::.:||.||:: ..::......:.:.|  |||.|::
Mosquito   846 SVGITKLLCECPEMLAEPYVLFWPQLLQTVVQIFELPPDE-SAIDGDNFIEIEDVP--GYQAAYS 907

  Fly   911 QLTHAQPNQQDHLAEIKDARQFLATSLSKFAQARAGEFSTLLSPLEPEYKQVLQKYCDQAGVRIA 975
            ||..||....|.|.::.:.||.|..:|.|.|||..|:..||::.|..::::.|||||.|:||:||
Mosquito   908 QLNFAQSKPVDPLPDVGNVRQHLVQNLGKLAQANGGKVRTLIAALPADHQEALQKYCAQSGVQIA 972

  Fly   976  975
            Mosquito   973  972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	48/75 (64%)
		Cse1	159..528	CDD:285678	262/368 (71%)
		CAS_CSE1	530..966	CDD:281384	238/435 (55%)
AgaP_AGAP010711	XP_311424.1	IBN_N	29..105	CDD:281761	48/75 (64%)
		Cse1	159..528	CDD:285678	262/368 (71%)
		CAS_CSE1	530..963	CDD:281384	238/435 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	546	1.000	Domainoid score	I925
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1006
Inparanoid	1	1.050	1267	1.000	Inparanoid score	I535
OMA	1	1.010	-	-		QHG53855
OrthoDB	1	1.010	-	-		D1248958at2759
OrthoFinder	1	1.000	-	-		FOG0004998
OrthoInspector	1	1.000	-	-		oto106902
Panther	1	1.100	-	-	LDO	PTHR10997
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3532
TreeFam	1	0.960	-	-
	13	12.940