Protein Alignment Cse1 and AgaP_AGAP011156

DIOPT Version :9

• Sequence 1: NP_523588.2
• Gene: Cse1 / 35016
• FlyBaseID: FBgn0022213
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_309493.3
• Gene: AgaP_AGAP011156 / 1270773
• VectorBaseID: AGAP011156
• Length: 1047
• Species: Anopheles gambiae
• Alignment Length: 1166
• Identity: 202/1166 - (17%)
• Similarity: 393/1166 - (33%)
• Gaps: 334/1166 - (28%)

  Fly     4 TEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLIDKAQMDMTTRVAGAIAFK 68
            ::|..|.:...||:.|..|.:.|:.||..|...:..:.|.:||.......|:.:..|...::..|
Mosquito     8 SDAVKQAMFEELQKILHPDSDQRKSAEARLAQLKFTEWYGVLLAEFTIDQQLHIGLRQLASVMLK 72

  Fly    69 NYIKRNWAAHLDSDGPDRIHES--------DRNTIKTLIVT------LMLHSPVALQKQLSDAVS 119
            .|:...||     ||.|.:.:.        |..|...|:|.      :....|..|..|.|...|
Mosquito    73 QYVNDCWA-----DGGDVVEDGGAGDLPAIDAGTTPALLVNDEAKRRIKQILPEGLYDQNSKIRS 132

  Fly   120 I-------IGKYDFPKKWPQLIDEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIK 177
            :       |..||:|..|.:|.|.:| :..||..|.::|.::    :...:..|...| :.|...
Mosquito   133 VVAYCIANIALYDWPGDWQELFDVIV-KCLSGTENSVDGAMK----VLVEFTLELDRQ-VGEVAP 191

  Fly   178 FVLDRMAKPLTDLLQATMQLTKVHENNAGALKVIYGSLVLVNKVFFSLNSQDLPEFFEDNINTWM 242
            .:|..:.:..|...|.::...|.      |::::|..|..:|....:...:..      .:|..:
Mosquito   192 LILSEVYRIFTAANQYSVTARKY------AVEILYSLLRSINTNIETRQEKSA------ILNPVL 244

  Fly   243 GAFIQQLAADVPSLRTADDEDAGVLEHLRAQVCENICLYAKKYDEEFKPFMEQFVTAVWELL--- 304
            ..|:|:|   :..|...:...:..  .|:.|:.:.:........:..:|::...:..:|:||
Mosquito   245 PNFMQRL---IEGLTAPNGPHSSF--QLKTQIIKILKYMISDMSKFVQPYVGTILPTIWQLLTQL 304

  Fly   305 ----VKTSLHTK-------------------YDSLVSHALQFLSVVADRQHYQSIFENPEILAQI 346
                ||..::..                   :..::....:|:..:.:.:.|::...|     .:
Mosquito   305 ADFYVKVVVNESEAAPFNGTDQDGDDDGVEDFTQMILQIFEFVHTIIEMKKYKAAIVN-----VL 364

  Fly   347 CDKVVIPNLDIRPSDEEIFE--DSPEEYIRRDIEGSDIDTRRRAACDLVKTLSINFEQKIFGIFG 409
            .|.|.|..|.::.::|:..:  :.||:::..:.|.....|.|..|.|::..:...:||::...|.
Mosquito   365 TDLVYITVLYMQITEEQAQQWLEDPEKFVDDEDEQGVEFTIRVTAHDVLLIVGREYEQQLLPCFT 429

  Fly   410 QYLER--LLTKYKENPATN---WRSKDTAIYLVTSWASRGGTQKHGITQTSELVPLPEFCAQQII 469
            :.|.:  .:.:...| |.|   |:..::::..|       |:.|..|.::.....:.::
Mosquito   430 EALGKHSAVAEVDRN-AGNPHWWKIHESSMLAV-------GSFKDMIVESPASFDMGQY------ 480

  Fly   470 PELERPNINEFPVLKAAAIKYVMVFRSILGPQVLASCLPQLIRHLPAESSVVHSYAACSVEKILS 534
                           .|.||  |:..|...|.:|..||..|.|           :..|.:.:...
Mosquito   481 ---------------LALIK--MLMESQASPYLLGRCLWLLSR-----------FCECDILRQPF 517

  Fly   535 MRDASNAIVFG-----PQILAPYTTELISGLFATLSLPGSGENEYVMKAIMRSF-----SVLQSA 589
            |....|..|..     |.:|.......|.|..:.|. ....|...::.:.:.:|     .:.:.:
Mosquito   518 MEQIVNVTVDSLSMDKPIVLRIMAARAIYGFCSNLK-DNKDERHVLIMSKLENFFDGLVGLFEQS 581

  Fly   590 AMPFMGVALPRLTEILTQVAKNPSRPQFNHYLFE---TLALCIKIVCHADSSAVSSFEEALFPVF 651
            ....:|:.|..|:.|::               |:   |..||.|::. ...:....|.:..|
Mosquito   582 QNTVLGLFLEALSAIIS---------------FDVNVTATLCPKVIT-VTMTVFQKFHDDRF--- 627

  Fly   652 QGILQQDIVEFMPYVFQMLS----VLLEMREGTGTIPEPYWALFPCLLSPALWDRTGN---VTPL 709
                   :||.:..|.::||    .||.:::          .:.|.|:|....|:.|:   :.|.
Mosquito   628 -------LVEMVQDVLKILSQNPFCLLPLQD----------RIIPTLVSILNHDQGGDQQTLAPD 675

  Fly   710 IRL--ISAFIKQGSAQIQALGKLSGILGIFQKMIAS----------KANDHE----GFYLLQNLL 758
            |.|  :...:|...|.:.            ..||.|          :..||.    |...|::.|
Mosquito   676 IALDVLQTLVKYSQAPLS------------DAMIESAFPSAVHCILRTEDHSVMQAGGECLRSFL 728

  Fly   759 SY-------YPPAEIQTNLRQIFGLLFQRLSLSKTPKYLSGIIIFFSFYVIKFSGSQMAQLID-- 814
            :.       |...|....:.|:..:|...::...|..::..::|    .:|...|:.:...:|
Mosquito   729 AIAPEQICRYKNGEGLNYVLQVTTMLLNPMNTESTASFIGRLVI----TIITKVGNLLGDSVDLL 789

  Fly   815 ---------------------EIQPNLFGMLLDRVFITEMGKIP--------------------- 837
                                 .|..:|..:.||.| :..:..:|
Mosquito   790 LKAVLSKMQLVKSLNVIMSLVTIFAHLILLQLDAV-MNFLSTVPGPTGETAMSFVLANWLSRQHL 853

  Fly   838 --KEQDRKMVAVGVTKLL----------TETPEILQQQYAT------------------------ 866
              .:.:||:..:.:.||.          ..|..|.:|..||
Mosquito   854 FYGQYERKVTTLALCKLFEHGVTTKDDRLNTVMIKEQVPATTPSGAAGNTGRRTRSASAKTPMVW 918

  Fly   867 --------FWPRLLHSLIDLFERPPEKLMGLEIGETAGVAEDPDAGYQVA--------FAQLTHA 915
                    .:..|||.|..|.|.........:.|:.|..:.|.:|..:|:        ...|||.
Mosquito   919 VDTPVLVKIFKLLLHELASLREAKDALNKNTDSGDEANSSSDEEAADEVSGDGGKMSFLTLLTHM 983

  Fly   916 QPNQQDH---LAEIK-------DARQFLATSLSKFAQARAGEFSTLLSPLEPEYKQVLQKY 966
            ....:|.   :||:.       |..::|...:..|:|..  .|...|..::...|.:||.:
Mosquito   984 DDEDEDDRQLMAELMNDPIFQCDTMEYLTKFIESFSQHE--NFRAFLEKIDETEKNILQTF 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cse1	NP_523588.2	IBN_N	29..105	CDD:281761	19/89 (21%)
		Cse1	159..528	CDD:285678	62/401 (15%)
		CAS_CSE1	530..966	CDD:281384	96/584 (16%)
AgaP_AGAP011156	XP_309493.3	CSE1	17..>414	CDD:227944	80/429 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810