Protein Alignment CG13280 and GFOD2

DIOPT Version :9

• Sequence 1: NP_609812.1
• Gene: CG13280 / 35015
• FlyBaseID: FBgn0032609
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_110446.3
• Gene: GFOD2 / 81577
• HGNCID: 28159
• Length: 385
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 74/357 - (20%)
• Similarity: 133/357 - (37%)
• Gaps: 68/357 - (19%)

  Fly   128 QSHALAFAERHQVENVYTS-FEDLAKCPNVDVVYISPLNPQHSELCHLMLNHDKHVLCEKPLCMT 191
            :..|...||...:. .||| .:|:....:||:|.||...|...::....|...|:|:|||  ..|
Human    38 EEEAKQLAEEMNIA-FYTSRTDDILLHQDVDLVCISIPPPLTRQISVKALGIGKNVVCEK--AAT 99

  Fly   192 EEQVTKLLEKAR-ARGLFLMEGMWPRCVPAYHYLRHQILRNRLGEI----KQVHCTLGLPVSQGR 251
            .....:::..:| ...|..:.|...|.:||:..::..|..:.:|.:    .:::....|..|.|.
Human   100 SVDAFRMVTASRYYPQLMSLVGNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGW 164

  Fly   252 LG---LYGGVTNDFGVYGMQLALWV----FREVPRCLKVSGRVNS-----EHV------------ 292
            :.   :.||..:..|.|.:.|...:    ..:|...||...|.|:     .||
Human   165 ICDELMGGGGLHTMGTYIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLM 229

  Fly   293 --DVSADIELCFTRGKRALIEV----SSEKKLSNQAVIQGKDGSIKMNNYWCPTRLITEEVDYEF 351
              .|.:.:.|.|......:.||    |:.:.::..|.:.|:..|......     |:.:.:....
Human   230 GGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEEL-----LLRDSLAVGA 289

  Fly   352 PLP-GGDQLPPTHYHNRLGMCYEAEEVRNCIL-KGSTESDD-------FSHNESLLLANLMDTIH 407
            .|| .|.|..|..|..  ||.|..:.:|.... :|...:.|       .|..:.|.:.:::|.|.
Human   290 GLPEQGPQDVPLLYLK--GMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIK 352

  Fly   408 AELGVGEFANRNEVSDLQKQIENVQDIVKDPE 439
            .....||:             |.|:.:.::|:
Human   353 RSSRSGEW-------------EAVEVLTEEPD 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13280	NP_609812.1	MviM	89..387	CDD:223745	64/296 (22%)
		GFO_IDH_MocA	92..213	CDD:279716	22/86 (26%)
GFOD2	NP_110446.3	MviM	1..364	CDD:223745	72/348 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0673
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810