DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13280 and gfod2

DIOPT Version :9

Sequence 1:	NP_609812.1	Gene:	CG13280 / 35015	FlyBaseID:	FBgn0032609	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001025591.1	Gene:	gfod2 / 594979	XenbaseID:	XB-GENE-5740207	Length:	384	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	89/420 - (21%)
Similarity:	138/420 - (32%)	Gaps:	136/420 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 GVWVVDEGPTLRWGIAPVSLM-ADDFAAALSVLPEQHHRIVSCVAAYQSHALAFAERHQVENVYT 145
            |:.|...|.|.|   ..:||: ||.|:            |.:........|...||...:.....
Frog     6 GIGVFGTGNTAR---VLISLLRADGFS------------IEALWGKTDEEAKELAEEMGIPFYTC 55

  Fly   146 SFEDLAKCPNVDVVYISPLNPQHSELCHLMLNHDKHVLCEKPL----CMTEEQVTKLLEKARARG 206
            ..:|:.....||:|.||...|...::....|...|:|:|||..    ..|..:..:...|
Frog    56 HTDDVLLHQEVDLVCISIPPPLTRQIAVKALGIGKNVICEKAASSIDAFTMVKAARYYPK----- 115

  Fly   207 LFLMEGMWPRCVPAYHYLRHQIL-RNRLGEIK--QVHCTLGLPVSQG-------RLGLYGGVTND 261
            |..:.|...|.:||:..:|..|| :|.:|||:  .|....|..:|..       .:|  ||..:.
Frog   116 LMSLVGNALRFLPAFDRMRQLILEQNYVGEIRICDVRVYGGSLLSSNYSWICDDLMG--GGGLHT 178

  Fly   262 FGVYGMQLALWVFREVPRCLKVSGRV-----NSEHVD----VSADIELCFTRGKRALIEVSSEKK 317
            .|.|.:.|...:..:  |..||.|.:     .:|.:.    |::| :.||.:
Frog   179 LGTYLVDLLTHLTNK--RAEKVHGFLKTFVKQNEAISGIRYVTSD-DFCFFQ------------- 227

  Fly   318 LSNQAVIQGKDGSIKMNNYWCPTRLITEEVDYEFPLPGGDQLPPTHYH--------NRLGMCYEA 374
                         ::|....|.|      |...|.:||      |..|        .||
Frog   228 -------------MQMTGGACST------VTLNFNMPG------TFVHEVMVVGSAGRL------ 261

  Fly   375 EEVRNCILKGSTESDDFSHNESLLLANLMDTIHAELGVGEFANRNEVSDLQKQIENVQDIVKDPE 439
             .||...|.|...|   :..|.|||::                     .|.::|.::.|..|.|.
Frog   262 -VVRGTELFGQKNS---ASEEKLLLSD---------------------PLTREIADISDFEKVPP 301

  Fly   440 ELASETCRVVEDISMGGRSLDINRQEVKDQ 469
            ........:|:.:          ||..:||
Frog   302 PYLMGIAHMVKAL----------RQSFQDQ 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13280	NP_609812.1	MviM	89..387	CDD:223745	72/329 (22%)
CG13280	NP_609812.1	GFO_IDH_MocA	92..213	CDD:279716	26/125 (21%)
gfod2	NP_001025591.1	MviM	1..365	CDD:223745	89/420 (21%)
		GFO_IDH_MocA	7..118	CDD:279716	29/130 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	358..384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910