DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13280 and CG3609

DIOPT Version :9

Sequence 1:	NP_609812.1	Gene:	CG13280 / 35015	FlyBaseID:	FBgn0032609	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001188684.1	Gene:	CG3609 / 33421	FlyBaseID:	FBgn0031418	Length:	335	Species:	Drosophila melanogaster

Alignment Length:	334	Identity:	128/334 - (38%)
Similarity:	192/334 - (57%)	Gaps:	23/334 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 LRWGIAPVSLMADDFAAALSVLPEQHHRIVSCVAAYQSHALAFAERHQVENVYTSFEDLAKCPNV 156
            :|||||....:::||..|||.||...|::.:..|.....|..||.:|.:.....|:|:|||..:|
  Fly     5 IRWGIASAGKISEDFVIALSTLPSSDHKVQAVAARALDRAQEFATKHGIPKALGSYEELAKSTDV 69

  Fly   157 DVVYISPLNPQHSELCHLMLNHDKHVLCEKPLCMTEEQVTKLLEKARARGLFLMEGMWPRCVPAY 221
            |||||..|||||.|:..||||:.|||||||||.|.::||..:|..|:|...|.||.:|.|..|:|
  Fly    70 DVVYIGTLNPQHYEVALLMLNNGKHVLCEKPLAMNKKQVEGILAAAKANKRFFMEAVWSRFFPSY 134

  Fly   222 HYLRHQILRNRLGEIKQVHCTLGLP------VSQGRLGLYGGVTNDFGVYGMQLALWVFREVPRC 280
            ..::..|...:||::|.|....|.|      :.:..||  |||..|.|:|.:|::.|.|:|.|..
  Fly   135 QRVKELISSGQLGQVKDVEVNFGFPMPHVDRLQKRELG--GGVVYDLGIYTIQVSQWAFQEKPEK 197

  Fly   281 LKVSGRVNSEHVDVSADIELCFTRGKRALIEVSSEKKLSNQAVIQGKDGSIKMNNYWCPTRLITE 345
            ::..|.:|:|.:|......|.::.|:.|.:..||::||.|.|||:|..|.:.:.::|.|.:||
  Fly   198 IESKGTLNAEGIDDDVSATLTYSGGRTARMRFSSKEKLGNTAVIKGTKGQVTLIDFWSPNKLI-- 260

  Fly   346 EVDYEFPLPGGDQ--LPP-----THYHNRLGMCYEAEEVRNCILKGSTESDDFSHNESLLLANLM 403
            ::|      |.::  |||     |:|.|...|.||||.||..|:.|..|:.:.::.:||:.|.:.
  Fly   261 DID------GQEKEWLPPKGKYATNYANSEAMRYEAEAVRQSIIAGEVENKNVTYADSLIFAEIE 319

  Fly   404 DTIHAELGV 412
            |||..::||
  Fly   320 DTIRKQIGV 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13280	NP_609812.1	MviM	89..387	CDD:223745	119/307 (39%)
CG13280	NP_609812.1	GFO_IDH_MocA	92..213	CDD:279716	57/120 (48%)
CG3609	NP_001188684.1	MviM	5..292	CDD:223745	114/296 (39%)
		GFO_IDH_MocA	5..123	CDD:279716	55/117 (47%)
		GFO_IDH_MocA_C	138..>198	CDD:304482	20/61 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473014
Domainoid	1	1.000	70	1.000	Domainoid score	I3394
eggNOG	1	0.900	-	-		E1_COG0673
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I2178
Isobase	1	0.950	-	0	Normalized mean entropy	S4313
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D351032at33208
OrthoFinder	1	1.000	-	-		FOG0001373
OrthoInspector	1	1.000	-	-		otm51331
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22604
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X868
	11	10.850