DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13280 and SPAC513.06c

DIOPT Version :9

Sequence 1:	NP_609812.1	Gene:	CG13280 / 35015	FlyBaseID:	FBgn0032609	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_593980.1	Gene:	SPAC513.06c / 2543473	PomBaseID:	SPAC513.06c	Length:	368	Species:	Schizosaccharomyces pombe

Alignment Length:	377	Identity:	113/377 - (29%)
Similarity:	159/377 - (42%)	Gaps:	82/377 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 PTLRWGIAPVSLMADDFAAALSVLPEQH---HRIVSCVAAYQSH-ALAFAERHQV---ENVYTSF 147
            |.:.||......:|..||..|..:||:|   |.||:.......| |.:||:.|..   ...|.|:
pombe     9 PVIHWGFLGAGSIAAVFAKDLVGVPERHKVQHEIVAVATRDSEHRASSFAKNHCAPCKPKAYGSY 73

  Fly   148 EDLAKCPNVDVVYISPLNPQHSELCHLMLNHDKHVLCEKPLCMTEEQVTKLLEKARARGLFLMEG 212
            |:|.|...||:||||..:|||.|:..|.|.:||.|||||||.:...:..:|:|.||||.||..||
pombe    74 EELVKDDKVDIVYISSTHPQHYEVVKLALLNDKAVLCEKPLTINYPEALELVELARARNLFFAEG 138

  Fly   213 MWPRCVPAYHYLRHQILRNRL-GEIKQVHCTLGLPVSQ----------GRL---GLYGGVTNDFG 263
            .|.|..|.....:..:..:|: |:    |..|.:..||          .||   .|..||..|.|
pombe   139 FWIRFYPIVKAAKTLLHEDRVCGD----HFRLFVDFSQDFRFRELPSESRLRTVSLGAGVLLDMG 199

  Fly   264 VYGMQLALWVFREVPRCLKVSGRVNSEHV---DVSADI------------------ELC--FTRG 305
            ||.:..:..:..:.|:..|....|:|..:   |.:.||                  .||  ..||
pombe   200 VYPLTWSRLLLYDDPKNEKQEPTVSSNALTFEDHNGDIGDYTTAVTLVFPKTESIAMLCTSMDRG 264

  Fly   306 KRA--LIEVSSEKKLSNQAVIQG---KDGSIKMNNYWCPTRLI-----TEEVDYEFPLPGGDQLP 360
            |.:  .:::..|.  .||..|.|   :..|||         ||     ||..|:.|
pombe   265 KMSDDFLKLDGEN--GNQLFISGDCYRPQSIK---------LIRASGETEVFDFSF--------- 309

  Fly   361 PTHYHNRLGMCYEAEEVRNCILKGSTESDDFSHNESLLLANLMDTIHAELGV 412
                .:..|..||.:.|..|:||...|:.:..|.|:|.:..|.|.|..::.|
pombe   310 ----DDATGFFYEQDAVAECLLKNMKEAPEIPHEETLKMMQLTDQIRRQINV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13280	NP_609812.1	MviM	89..387	CDD:223745	105/350 (30%)
CG13280	NP_609812.1	GFO_IDH_MocA	92..213	CDD:279716	52/127 (41%)
SPAC513.06c	NP_593980.1	MviM	8..355	CDD:223745	112/373 (30%)
SPAC513.06c	NP_593980.1	GFO_IDH_MocA	11..139	CDD:279716	52/127 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2037
eggNOG	1	0.900	-	-		E1_COG0673
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1364
OMA	1	1.010	-	-		QHG57478
OrthoFinder	1	1.000	-	-		FOG0001373
OrthoInspector	1	1.000	-	-		otm47012
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22604
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X868
TreeFam	1	0.960	-	-
	11	10.930