DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17928 and Fads2

DIOPT Version :9

Sequence 1:	NP_001260515.1	Gene:	CG17928 / 35009	FlyBaseID:	FBgn0032603	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_112634.1	Gene:	Fads2 / 83512	RGDID:	68339	Length:	444	Species:	Rattus norvegicus

Alignment Length:	447	Identity:	92/447 - (20%)
Similarity:	165/447 - (36%)	Gaps:	105/447 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PSYR----QHRPITSESWLEGKNVDDEAEGLWRINDTLYDLSDFAARHPGGSSWIECTRGTDITE 81
            |::|    |...:.::.||.             |:..:|:::.::.|||||...|....|.|.|:
  Rat    19 PTFRWEEIQKHNLRTDRWLV-------------IDRKVYNVTKWSQRHPGGHRVIGHYSGEDATD 70

  Fly    82 PFESHHIEERARGMLSKFEVRKAARPRNYKFTLEENGFYMTLKRRVREKLRKIDYSPTKKTE--- 143
            .|.:.|::....|...|..:.....|       ||.........::.|     |:...|||.
  Rat    71 AFRAFHLDLDFVGKFLKPLLIGELAP-------EEPSLDRGKSSQITE-----DFRALKKTAEDM 123

  Fly   144 ----------FL---HLGILVSV--FLFS-----WAGTVLDSLIF---KGLAGLALCWVATSTHN 185
                      ||   |:.::.|:  |:.|     |..||:.:.:.   :..||    |:   .|:
  Rat   124 NLFKTNHLFFFLLLSHIIVMESIAWFILSYFGNGWIPTVITAFVLATSQAQAG----WL---QHD 181

  Fly   186 YFH----QRDSWRMYTFNLTMMNFR----NWRISHALSHHVYAN---------SLHDLEMSMFEP 233
            |.|    ::..|........:.:.:    ||.......||...|         |||...:..::|
  Rat   182 YGHLSVYKKSIWNHIVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDIKSLHVFVLGEWQP 246

  Fly   234 F------LCWIPDSHYASKPQRLISVVISPVVYVVLFQGQFLIRLVLSLTKRNVLCWDDL---IG 289
            .      |.::|.:|     |.....:|.|.:.:.::   |..::::::.:|.  .|.||   |.
  Rat   247 LEYGKKKLKYLPYNH-----QHEYFFLIGPPLLIPMY---FQYQIIMTMIRRR--DWVDLAWAIS 301

  Fly   290 FSLPIFIYLSTGVSLLSALLSWEIIISVGSFIFGLVGLTAAHHDPRILHDGDAQRQDFDWGLYQV 354
            :....|........:|.||:....|..:.|..|  |.:|..:|   |:.:.|..... ||...|:
  Rat   302 YYARFFYTYIPFYGILGALVFLNFIRFLESHWF--VWVTQMNH---IVMEIDLDHYR-DWFSSQL 360

  Fly   355 DTIIDRGDIKWSDLLVLTHFGEHALHHLFPTLDHGVLKHLYPELRKTMKEFDVELRE 411
            ....:.....::|.. ..|......||||||:....|..:.|.::....:..:|.:|
  Rat   361 AATCNVEQSFFNDWF-SGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQE 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17928	NP_001260515.1	Cyt-b5	33..103	CDD:278597	17/69 (25%)
		Membrane-FADS-like	151..388	CDD:294412	57/272 (21%)
		FA_desaturase	171..412	CDD:278890	55/267 (21%)
Fads2	NP_112634.1	PLN03198	20..435	CDD:178739	91/446 (20%)
		Delta6-FADS-like	162..412	CDD:239583	54/273 (20%)
		Histidine box-1	180..184		2/3 (67%)
		Histidine box-2	217..221		0/3 (0%)
		Histidine box-3	382..386		0/3 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I5335
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060606at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.870