Protein Alignment CG17928 and FADS1

DIOPT Version :10

• Sequence 1: NP_609810.1
• Gene: CG17928 / 35009
• FlyBaseID: FBgn0032603
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_037534.5
• Gene: FADS1 / 3992
• HGNCID: 3574
• Length: 501
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 99/439 - (22%)
• Similarity: 170/439 - (38%)
• Gaps: 118/439 - (26%)

  Fly    28 PITSESWLEGKNV-----DDEA-----EGLWRIND-TLYDLSDFAARHPGGSSWIECTRGTDITE 81
            |:.:|:..:|...     |:.|     |..|.:.| .:|::|:|..||||||..|....|.|.|:
Human    62 PVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATD 126

  Fly    82 PFESHHIEERARGMLSKFEVRKAARPRNY----KFTLEENGFYMTLKRRVREKLRKIDYSPTKKT 142
            ||.:.||.   :|::.|:        .|.    :.:.|:..|..|..:.:.::.|::      :.
Human   127 PFVAFHIN---KGLVKKY--------MNSLLIGELSPEQPSFEPTKNKELTDEFREL------RA 174

  Fly   143 EFLHLGILVS--VFLFSWAGTVLDSLIFKGLAGLALCWVATSTHNYF----------HQRDSWRM 195
            ....:|::.:  ||...:   :|..|:..|.|.|.| ||..::...|          ..:..|..
Human   175 TVERMGLMKANHVFFLLY---LLHILLLDGAAWLTL-WVFGTSFLPFLLCAVLLSAVQAQAGWLQ 235

  Fly   196 YTF-NLTMMNFRNWRISHALSHHV----------YANSLH------------DLEMSMFEPFLC- 236
            :.| :|::.:...|  :|.|.|.|          :.|.:|            |.:::| .||..
Human   236 HDFGHLSVFSTSKW--NHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINM-HPFFFA 297

  Fly   237 ---------------WIPDSHYASKPQRLISVVISPVVYVVLFQGQFLIRLVLSLTKRNVLCWDD 286
                           ::|.:|     |.....:|.|...:.|:...::...|:...|...|.|
Human   298 LGKILSVELGKQKKKYMPYNH-----QHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAW-- 355

  Fly   287 LIGFSLPIFIYLSTGVSL--LSALLSWEIIISVGSFIFG--LVGLTAAHHDP-RILHDGDAQRQD 346
            :|.|.:..|:   |.|.|  |.|.|....|:   .|:..  .|.:|..:|.| .|.||     ::
Human   356 MITFYVRFFL---TYVPLLGLKAFLGLFFIV---RFLESNWFVWVTQMNHIPMHIDHD-----RN 409

  Fly   347 FDWGLYQVDTIIDRGDIKWSDLLVLTHFGEHALHHLFPTLDHGVLKHLY 395
            .||...|:....:.....::|.. ..|......||||||:.    :|.|
Human   410 MDWVSTQLQATCNVHKSAFNDWF-SGHLNFQIEHHLFPTMP----RHNY 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17928	NP_609810.1	Cyt-b5	42..105	CDD:459698	23/68 (34%)
		DesA	111..427	CDD:442471	71/341 (21%)
FADS1	NP_037534.5	PRK07003	<3..>75	CDD:235906	3/12 (25%)
		PLN03199	74..496	CDD:178740	96/427 (22%)
		Delta6-FADS-like	218..469	CDD:239583	55/262 (21%)