DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17928 and Cyt-b5-r

DIOPT Version :9

Sequence 1:	NP_001260515.1	Gene:	CG17928 / 35009	FlyBaseID:	FBgn0032603	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001260514.1	Gene:	Cyt-b5-r / 35008	FlyBaseID:	FBgn0000406	Length:	436	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	240/432 - (55%)
Similarity:	301/432 - (69%)	Gaps:	2/432 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DWRVSGISRNYPSYRQHRPITSESWLEGKNVDDEAEGLWRINDTLYDLSDFAARHPGGSSWIECT 74
            :|:.|||:..:|:||....||:.||.:||..||.|||||||||.:||.:.|..:||||..||..|
  Fly     5 EWKKSGIATKFPTYRNSALITTHSWQKGKRQDDGAEGLWRINDGIYDFTSFIDKHPGGPFWIRET 69

  Fly    75 RGTDITEPFESHHIEERARGMLSKFEVRKAARPRNYKFTLEENGFYMTLKRRVREKLRKIDYSPT 139
            :||||||.||:||:......|::|::||.||.||.|..||||.|||.|||.||||:|:.||..|.
  Fly    70 KGTDITEAFEAHHLTTAPEKMIAKYKVRDAAEPRIYTLTLEEGGFYKTLKERVREQLKTIDKRPK 134

  Fly   140 KKTEFLHLGILVSVFLFSWAGTVLDSLIFKGLAGLALCWVATSTHNYFHQRDSWRMYTFNLTMMN 204
            ||::.:|||::||::|...|....:||:...||.:||||....:|||||:||:|:||.|||.|||
  Fly   135 KKSDLIHLGLVVSLYLLGIASAKYNSLLALVLASVALCWTVIVSHNYFHRRDNWQMYAFNLGMMN 199

  Fly   205 FRNWRISHALSHHVYANSLHDLEMSMFEPFLCWIPDSHYASKPQRLISVVISPVVYVVLFQGQFL 269
            |..||:|||||||:|.||..|||:|||||.|||:|:.|..||..|.:|.|..||.|.:.|..|..
  Fly   200 FAAWRVSHALSHHIYPNSYFDLELSMFEPLLCWVPNPHIKSKLMRYVSWVTEPVAYALAFFIQMG 264

  Fly   270 IRLVLSLTKRNVLCWDDLIGFSLPIFIYLSTGVSL--LSALLSWEIIISVGSFIFGLVGLTAAHH 332
            .|:..||...|:|.|.||:..::||.|||.||.||  ...:..|..:.|:.||.|.|:||.||||
  Fly   265 TRIFYSLRHTNILYWHDLLPLTIPIAIYLGTGGSLGIWICVRQWLAMTSIASFSFCLIGLNAAHH 329

  Fly   333 DPRILHDGDAQRQDFDWGLYQVDTIIDRGDIKWSDLLVLTHFGEHALHHLFPTLDHGVLKHLYPE 397
            ||.|.|:|||.|:|.||||:||||||||||:|||..|||||||:|.|||||||||||:|..|||.
  Fly   330 DPEIYHEGDANREDRDWGLFQVDTIIDRGDLKWSQFLVLTHFGDHVLHHLFPTLDHGLLPALYPV 394

  Fly   398 LRKTMKEFDVELREINHWSHIKGQNQQLLRTEKNPIPPGSKK 439
            |.:|:.||...|||.||..|:.||::||||.|.||..||:.|
  Fly   395 LYQTLDEFKGHLRECNHIEHMIGQHKQLLRIEPNPRAPGAGK 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17928	NP_001260515.1	Cyt-b5	33..103	CDD:278597	38/69 (55%)
		Membrane-FADS-like	151..388	CDD:294412	135/238 (57%)
		FA_desaturase	171..412	CDD:278890	142/242 (59%)
Cyt-b5-r	NP_001260514.1	Cyt-b5	26..98	CDD:278597	38/71 (54%)
		FA_desaturase	161..408	CDD:278890	142/246 (58%)
		Membrane-FADS-like	<328..385	CDD:294412	44/56 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456655
Domainoid	1	1.000	260	1.000	Domainoid score	I4578
eggNOG	1	0.900	-	-		E1_COG3239
Homologene	1	1.000	-	-		H43205
Inparanoid	1	1.050	45	1.000	Inparanoid score	I2674
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58866
OrthoDB	1	1.010	-	-		D1060606at2759
OrthoFinder	1	1.000	-	-		FOG0012745
OrthoInspector	1	1.000	-	-		mtm9664
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR16740
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11811
	12	11.910